-transparent.png){kind=logo}
The primary structure of 22 N-terminal amino acid residues of placental protein 14 was determined by automated Edman degradation with a gas-phase sequencer. This protein, isolated from the human placenta and its membranes, was considered pure as evidenced by a single N-terminal amino acid sequence M D I P Q T K Q D L E L P K L A G T W H S M. It shows significant sequence homology with horse, bovine, buffalo, sheep and goat beta-lactoglobulins. We found 13 identities out of 22 possible matches with horse beta-lactoglobulin. beta-lactoglobulins from several animal species have been found to bind retinol. Among the identical residues there is one tryptophan at position 19 which is conserved in beta-lactoglobulins and is also found in the human retinol-binding protein at the corresponding position. These data suggest a common origin of PP14 and beta-lactoglobulins.
M L Huhtala, and
M Seppälä, and
A Närvänen, and
P Palomäki, and
M Julkunen, and
H Bohn
December 1988,
Proceedings of the National Academy of Sciences of the United States of America,
M L Huhtala, and
M Seppälä, and
A Närvänen, and
P Palomäki, and
M Julkunen, and
H Bohn
August 1984,
The Biochemical journal,
M L Huhtala, and
M Seppälä, and
A Närvänen, and
P Palomäki, and
M Julkunen, and
H Bohn
January 1985,
Comparative biochemistry and physiology. B, Comparative biochemistry,
M L Huhtala, and
M Seppälä, and
A Närvänen, and
P Palomäki, and
M Julkunen, and
H Bohn
May 1962,
Biochemical and biophysical research communications,
M L Huhtala, and
M Seppälä, and
A Närvänen, and
P Palomäki, and
M Julkunen, and
H Bohn
April 1981,
The Journal of clinical investigation,
M L Huhtala, and
M Seppälä, and
A Närvänen, and
P Palomäki, and
M Julkunen, and
H Bohn
March 1979,
Journal of theoretical biology,
M L Huhtala, and
M Seppälä, and
A Närvänen, and
P Palomäki, and
M Julkunen, and
H Bohn
October 1988,
FEBS letters,
M L Huhtala, and
M Seppälä, and
A Närvänen, and
P Palomäki, and
M Julkunen, and
H Bohn
January 1990,
FEBS letters,
M L Huhtala, and
M Seppälä, and
A Närvänen, and
P Palomäki, and
M Julkunen, and
H Bohn
October 1971,
FEBS letters,
M L Huhtala, and
M Seppälä, and
A Närvänen, and
P Palomäki, and
M Julkunen, and
H Bohn
July 1983,
Biochemical and biophysical research communications,
