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Of the results obtained by numerous investigators in the study of the acetylcholine-acetylcholinesterase system, it is quite clear that it is altered significantly in the convulsive state. In the present work, a study of the acetylcholinesterase activity (AChE) in serum was made in 53 patients with different type of epilepsy during the intercritical period. A significantly high increase in the enzymatic activity (p less than 0.001) was found, compared with that of the controls, unrelated with the probable etiology of the process nor with some symptoms. We observed, nevertheless, a tendency towards diminished enzymatic activity with an increase of the severity of the electroencephalographic picture, and we interpreted this as a compensating effect. The AChE activity in serum and cerebrospinal fluid of a group of epileptic patients subjected to stereotaxic operations was studied before and after surgery, observing a significantly diminished activity of AChE in serum (p less than 0.001) after surgery. This asserts the hypothesis of the compensating increase of the AChE activity in serum, which tends to normalize once some of the factors producing the decompensation are eliminated.
N Serguienko, and
A González-Quevedo, and
N González Pérez, and
L Simón y Cantón, and
G Marín Fernández
January 1951,
Journal of neuropathology and clinical neurology,
N Serguienko, and
A González-Quevedo, and
N González Pérez, and
L Simón y Cantón, and
G Marín Fernández
January 2014,
Clinical and experimental obstetrics & gynecology,
N Serguienko, and
A González-Quevedo, and
N González Pérez, and
L Simón y Cantón, and
G Marín Fernández
July 1952,
La Prensa medica mexicana,
N Serguienko, and
A González-Quevedo, and
N González Pérez, and
L Simón y Cantón, and
G Marín Fernández
May 1972,
Minerva medica,
N Serguienko, and
A González-Quevedo, and
N González Pérez, and
L Simón y Cantón, and
G Marín Fernández
June 2019,
Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia,
N Serguienko, and
A González-Quevedo, and
N González Pérez, and
L Simón y Cantón, and
G Marín Fernández
March 1966,
British journal of pharmacology and chemotherapy,
N Serguienko, and
A González-Quevedo, and
N González Pérez, and
L Simón y Cantón, and
G Marín Fernández
July 1970,
Indian journal of pediatrics,
N Serguienko, and
A González-Quevedo, and
N González Pérez, and
L Simón y Cantón, and
G Marín Fernández
November 2005,
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology,
N Serguienko, and
A González-Quevedo, and
N González Pérez, and
L Simón y Cantón, and
G Marín Fernández
August 2018,
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia,
N Serguienko, and
A González-Quevedo, and
N González Pérez, and
L Simón y Cantón, and
G Marín Fernández
January 1979,
Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952),
