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The migration activity of the spleen cells from intact mice is inhibited by the stem cell inhibitory factor (SCIF) released by lymphocytes treated with antilymphocytic globulin. The degree of the migration inhibition is proportional to the activity of SCIF in the colony-formation inhibition. The macrophage-migration inhibitory factor (MIF), obtained in the H-2 system exhibited a stimulating effect on the colony formation in mice when used in vitro for the treatment of bone marrow transplants. This activity of MIF corresponds to its migration-inhibitory effect on the spleen cells. Incubation of the bone marrow cells with MIF for 30 minutes is more effective than the 2-hour treatment. The observed effects are interpreted as an indication of non-identity of SCIF and MIF.
E B Mysiakin, and
A P Suslov, and
T A Golovanova, and
D R Kaulen
December 1980,
Immunobiology,
E B Mysiakin, and
A P Suslov, and
T A Golovanova, and
D R Kaulen
January 1977,
Uspekhi sovremennoi biologii,
E B Mysiakin, and
A P Suslov, and
T A Golovanova, and
D R Kaulen
January 1977,
Uspekhi sovremennoi biologii,
E B Mysiakin, and
A P Suslov, and
T A Golovanova, and
D R Kaulen
February 1972,
The Journal of experimental medicine,
E B Mysiakin, and
A P Suslov, and
T A Golovanova, and
D R Kaulen
February 1976,
The Journal of parasitology,
E B Mysiakin, and
A P Suslov, and
T A Golovanova, and
D R Kaulen
July 1974,
Immunology,
E B Mysiakin, and
A P Suslov, and
T A Golovanova, and
D R Kaulen
January 1978,
Microbiology and immunology,
E B Mysiakin, and
A P Suslov, and
T A Golovanova, and
D R Kaulen
February 1980,
Indian journal of experimental biology,
E B Mysiakin, and
A P Suslov, and
T A Golovanova, and
D R Kaulen
December 1980,
Zhurnal mikrobiologii, epidemiologii i immunobiologii,
E B Mysiakin, and
A P Suslov, and
T A Golovanova, and
D R Kaulen
January 1979,
Archivum immunologiae et therapiae experimentalis,
