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Phospholipid composition was studied in liver mitochondrial membranes of rats consuming ethanol for a long time. A new phospholipid phosphatidyl ethanol was found in the membranes, which appears to be formed due to the action of endogenous phospholipase D. The phospholipase D activity was measured in mitochondria using direct evaluation. Administration of ethanol led to alteration in the ratio of mitochondrial phospholipids.
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