BIOMAT Database Logo BIOMAT Database Logo

Modulation of the structural information in shape-defined heterocyclic strands: the case of a (pyridine-hydrazone)2pyrazine ligand. 2022

Muthu Kumar Thangavel, and Jack Harrowfield, and Corinne Bailly, and Lydia Karmazin, and Adrian-Mihail Stadler
Institut de Chimie, Université de Strasbourg, Strasbourg, France.

Metal ions (Ag+, Cd2+, Eu3+, Sm3+) and protons can, through coordination and protonation, modulate in three specific ways the structural information contained in the pyrazine-based heterocyclic strand L (obtained from 2,5-bis(methylhydrazino)pyrazine and 2 equivalents of 2-pyridinecarboxaldehyde), thus generating two linear rod-like conformations and a bent one. This conformational diversity is associated with a structural one that consists of two diprotonated forms (H2L(PF6)2 and H2L(CF3SO3)2), a polymeric architecture [AgL](CF3SO3), two rack-like complexes ([Eu2H2L3(CF3SO3)6](PF6)2 and [Sm2H2L3(CF3SO3)6](PF6)2) and a grid-like structure ([Cd4L4](CF3SO3)8).

UI MeSH Term Description Entries
D008024 Ligands A molecule that binds to another molecule, used especially to refer to a small molecule that binds specifically to a larger molecule, e.g., an antigen binding to an antibody, a hormone or neurotransmitter binding to a receptor, or a substrate or allosteric effector binding to an enzyme. Ligands are also molecules that donate or accept a pair of electrons to form a coordinate covalent bond with the central metal atom of a coordination complex. (From Dorland, 27th ed) Ligand
D008958 Models, Molecular Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures. Molecular Models,Model, Molecular,Molecular Model
D011522 Protons Stable elementary particles having the smallest known positive charge, found in the nuclei of all elements. The proton mass is less than that of a neutron. A proton is the nucleus of the light hydrogen atom, i.e., the hydrogen ion. Hydrogen Ions,Hydrogen Ion,Ion, Hydrogen,Ions, Hydrogen,Proton
D011719 Pyrazines A heterocyclic aromatic organic compound with the chemical formula C4H4N2. Pyrazine
D011725 Pyridines Compounds with a six membered aromatic ring containing NITROGEN. The saturated version is PIPERIDINES.
D002104 Cadmium An element with atomic symbol Cd, atomic number 48, and atomic weight 112.41. It is a metal and ingestion will lead to CADMIUM POISONING.
D006835 Hydrazones Compounds of the general formula R:N.NR2, as resulting from the action of hydrazines with aldehydes or ketones. (Grant & Hackh's Chemical Dictionary, 5th ed) Hydrazone
D018360 Crystallography, X-Ray The study of crystal structure using X-RAY DIFFRACTION techniques. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) X-Ray Crystallography,Crystallography, X Ray,Crystallography, Xray,X Ray Crystallography,Xray Crystallography,Crystallographies, X Ray,X Ray Crystallographies

Related Publications

Muthu Kumar Thangavel, and Jack Harrowfield, and Corinne Bailly, and Lydia Karmazin, and Adrian-Mihail Stadler
Hydrazone Photoswitches for Structural Modulation of Short Peptides.
February 2022, Chemistry (Weinheim an der Bergstrasse, Germany),
Muthu Kumar Thangavel, and Jack Harrowfield, and Corinne Bailly, and Lydia Karmazin, and Adrian-Mihail Stadler
Shape-Memory Metallopolymer Networks Based on a Triazole-Pyridine Ligand.
November 2019, Polymers,
Muthu Kumar Thangavel, and Jack Harrowfield, and Corinne Bailly, and Lydia Karmazin, and Adrian-Mihail Stadler
Structural codons: linearity/helicity interconversion by pyridine/pyrimidine exchange in molecular strands.
January 2004, Chemical communications (Cambridge, England),
Muthu Kumar Thangavel, and Jack Harrowfield, and Corinne Bailly, and Lydia Karmazin, and Adrian-Mihail Stadler
Enhanced π-back-donation resulting in the trans labilization of a pyridine ligand in an N-heterocyclic carbene (NHC) PdII precatalyst: a case study.
July 2019, Acta crystallographica. Section C, Structural chemistry,
Muthu Kumar Thangavel, and Jack Harrowfield, and Corinne Bailly, and Lydia Karmazin, and Adrian-Mihail Stadler
Synthesis and structural characterisation of stable pyridine- and phosphine-functionalised N-heterocyclic carbenes.
March 2002, Chemical communications (Cambridge, England),
Muthu Kumar Thangavel, and Jack Harrowfield, and Corinne Bailly, and Lydia Karmazin, and Adrian-Mihail Stadler
Design of High-Performance Pyridine/Quinoline Hydrazone Photoswitches.
September 2021, The Journal of organic chemistry,
Muthu Kumar Thangavel, and Jack Harrowfield, and Corinne Bailly, and Lydia Karmazin, and Adrian-Mihail Stadler
Electronic Structure Determination of Pyridine N-Heterocyclic Carbene Iron Dinitrogen Complexes and Neutral Ligand Derivatives.
October 2014, Organometallics,
Muthu Kumar Thangavel, and Jack Harrowfield, and Corinne Bailly, and Lydia Karmazin, and Adrian-Mihail Stadler
Is genetic code redundancy related to retention of structural information in both DNA strands?
July 1990, Trends in biochemical sciences,
Muthu Kumar Thangavel, and Jack Harrowfield, and Corinne Bailly, and Lydia Karmazin, and Adrian-Mihail Stadler
Synthesis and structural characterisation of the first N-heterocyclic carbene ligand fused to a porphyrin.
June 2007, Chemical communications (Cambridge, England),
Muthu Kumar Thangavel, and Jack Harrowfield, and Corinne Bailly, and Lydia Karmazin, and Adrian-Mihail Stadler
Structural basis for ligand modulation of the CCR2 conformational landscape.
April 2019, Proceedings of the National Academy of Sciences of the United States of America,
Copied contents to your clipboard!