-transparent.png){kind=logo}
In attempts to produce stable lines secreting bovine monoclonal antibodies, murine/bovine hybridomas (1 degree xenohybridomas) were selectively cultured in 8-azaguanine to derive HAT-sensitive lines that were then used as myeloma partners for further fusions with bovine lymphocytes. The resulting 2 degrees xenohybridomas were further selected to produce 3 degrees xenohybridomas. Four stable lines secreting bovine monoclonal antibodies recognizing blood group determinants X1 (an IgG1), E'2 (an IgM) and SU" (an IgGI) and another (an IgGI) as yet unidentified were produced from fusions of 2 degrees xenohybridomas with lymphocytes from calves that had been immunized with bovine red cells.
E M Tucker, and
S W Clarke, and
L Méténier
January 1992,
Animal genetics,
E M Tucker, and
S W Clarke, and
L Méténier
January 1993,
Experimental and clinical immunogenetics,
E M Tucker, and
S W Clarke, and
L Méténier
January 1988,
Folia biologica,
E M Tucker, and
S W Clarke, and
L Méténier
November 1983,
Journal of immunology (Baltimore, Md. : 1950),
E M Tucker, and
S W Clarke, and
L Méténier
March 1985,
Molekuliarnaia genetika, mikrobiologiia i virusologiia,
E M Tucker, and
S W Clarke, and
L Méténier
January 1985,
Voprosy virusologii,
E M Tucker, and
S W Clarke, and
L Méténier
January 1994,
Investigative urology (Berlin, Germany),
E M Tucker, and
S W Clarke, and
L Méténier
March 1983,
Science (New York, N.Y.),
E M Tucker, and
S W Clarke, and
L Méténier
January 1985,
Cellular immunology,
E M Tucker, and
S W Clarke, and
L Méténier
June 1987,
Veterinary immunology and immunopathology,
