-transparent.png){kind=logo}
All trans retinoic acid inhibited diferric transferrin reduction by HeLa cells. The NADH diferric transferrin reductase activity of isolated liver plasma membranes was also inhibited by retinoic acid. Retinol and retinyl acetate had very little effect. Transplasma membrane ferricyanide reduction by HeLa cells and NADH ferricyanide reductase of liver plasma membrane was also inhibited by retinoic acid, therefore the inhibition was in the electron transport system and not at the transferrin receptor. Since the transmembrane electron transport has been shown to stimulate cell growth, the growth inhibition by retinoic acid thus may be based on inhibition of the NADH diferric transferrin reductase.
I L Sun, and
W Toole-Simms, and
F L Crane, and
E S Golub, and
T Díaz de Pagán, and
D J Morré, and
H Löw
September 1986,
Biochemical and biophysical research communications,
I L Sun, and
W Toole-Simms, and
F L Crane, and
E S Golub, and
T Díaz de Pagán, and
D J Morré, and
H Löw
November 1987,
The Journal of biological chemistry,
I L Sun, and
W Toole-Simms, and
F L Crane, and
E S Golub, and
T Díaz de Pagán, and
D J Morré, and
H Löw
January 1989,
Biochemical and biophysical research communications,
I L Sun, and
W Toole-Simms, and
F L Crane, and
E S Golub, and
T Díaz de Pagán, and
D J Morré, and
H Löw
January 1987,
Biochemistry international,
I L Sun, and
W Toole-Simms, and
F L Crane, and
E S Golub, and
T Díaz de Pagán, and
D J Morré, and
H Löw
April 1990,
Biochimica et biophysica acta,
I L Sun, and
W Toole-Simms, and
F L Crane, and
E S Golub, and
T Díaz de Pagán, and
D J Morré, and
H Löw
December 2004,
Blood,
I L Sun, and
W Toole-Simms, and
F L Crane, and
E S Golub, and
T Díaz de Pagán, and
D J Morré, and
H Löw
January 2012,
Biochemistry research international,
I L Sun, and
W Toole-Simms, and
F L Crane, and
E S Golub, and
T Díaz de Pagán, and
D J Morré, and
H Löw
September 1990,
The Journal of biological chemistry,
I L Sun, and
W Toole-Simms, and
F L Crane, and
E S Golub, and
T Díaz de Pagán, and
D J Morré, and
H Löw
January 1981,
Proceedings of the National Academy of Sciences of the United States of America,
I L Sun, and
W Toole-Simms, and
F L Crane, and
E S Golub, and
T Díaz de Pagán, and
D J Morré, and
H Löw
December 2009,
The protein journal,
