Sensorineural hearing loss after neonatal meningitis: a single-centre retrospective study. 2022

Ankur Sharma, and James M Leaf, and Saumya Thomas, and Christine Cane, and Claire Stuart, and Catherine Tremlett, and John Fitzgerald, and Paul Clarke
Neonatal Intensive Care Unit, Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich, UK.

Babies in intensive care are at higher risk for meningitis and sensorineural hearing loss (SNHL). We reviewed the rate of SNHL among definite cases of bacterial/fungal meningitis in our neonatal intensive care unit over a 16-year period (2006-2021). We identified 16 confirmed meningitis cases among 16 070 admissions: 8 of 10 surviving infants with available diagnostic audiology had normal/satisfactory hearing while 2 of 10 had SNHL. Both infants with permanent hearing loss had been born extremely preterm and received potentially ototoxic antimicrobials. Larger studies are needed to clarify whether SNHL occurs mainly due to meningitis itself or to its antimicrobial drug treatment.

UI MeSH Term Description Entries
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D007232 Infant, Newborn, Diseases Diseases of newborn infants present at birth (congenital) or developing within the first month of birth. It does not include hereditary diseases not manifesting at birth or within the first 30 days of life nor does it include inborn errors of metabolism. Both HEREDITARY DISEASES and METABOLISM, INBORN ERRORS are available as general concepts. Neonatal Diseases,Disease, Neonatal,Diseases, Neonatal,Neonatal Disease
D003638 Deafness A general term for the complete loss of the ability to hear from both ears. Deafness Permanent,Hearing Loss Permanent,Prelingual Deafness,Deaf Mutism,Deaf-Mutism,Deafness, Acquired,Hearing Loss, Complete,Hearing Loss, Extreme,Acquired Deafness,Complete Hearing Loss,Deafness, Prelingual,Extreme Hearing Loss,Permanent, Deafness,Permanent, Hearing Loss,Permanents, Deafness
D006319 Hearing Loss, Sensorineural Hearing loss resulting from damage to the COCHLEA and the sensorineural elements which lie internally beyond the oval and round windows. These elements include the AUDITORY NERVE and its connections in the BRAINSTEM. Deafness Neurosensory,Deafness, Neurosensory,Deafness, Sensoryneural,Neurosensory Deafness,Sensorineural Hearing Loss,Sensoryneural Deafness,Cochlear Hearing Loss,Hearing Loss, Cochlear,Deafnesses, Neurosensory,Deafnesses, Sensoryneural,Neurosensory Deafnesses,Sensoryneural Deafness,Sensoryneural Deafnesses
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012189 Retrospective Studies Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons. Retrospective Study,Studies, Retrospective,Study, Retrospective
D015997 Neonatal Screening The identification of selected parameters in newborn infants by various tests, examinations, or other procedures. Screening may be performed by clinical or laboratory measures. A screening test is designed to sort out healthy neonates (INFANT, NEWBORN) from those not well, but the screening test is not intended as a diagnostic device, rather instead as epidemiologic. Infant, Newborn, Screening,Newborn Infant Screening,Newborn Screening,Neonatal Screenings,Newborn Infant Screenings,Newborn Screenings,Screening, Neonatal,Screening, Newborn,Screening, Newborn Infant,Screenings, Neonatal,Screenings, Newborn,Screenings, Newborn Infant
D016920 Meningitis, Bacterial Bacterial infections of the leptomeninges and subarachnoid space, frequently involving the cerebral cortex, cranial nerves, cerebral blood vessels, spinal cord, and nerve roots. Bacterial Meningitis,Bacterial Meningitides,Meningitides, Bacterial

Related Publications

Ankur Sharma, and James M Leaf, and Saumya Thomas, and Christine Cane, and Claire Stuart, and Catherine Tremlett, and John Fitzgerald, and Paul Clarke
January 2022, Acta oto-laryngologica,
Ankur Sharma, and James M Leaf, and Saumya Thomas, and Christine Cane, and Claire Stuart, and Catherine Tremlett, and John Fitzgerald, and Paul Clarke
July 1985, The Laryngoscope,
Ankur Sharma, and James M Leaf, and Saumya Thomas, and Christine Cane, and Claire Stuart, and Catherine Tremlett, and John Fitzgerald, and Paul Clarke
July 2003, Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology,
Ankur Sharma, and James M Leaf, and Saumya Thomas, and Christine Cane, and Claire Stuart, and Catherine Tremlett, and John Fitzgerald, and Paul Clarke
April 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology,
Ankur Sharma, and James M Leaf, and Saumya Thomas, and Christine Cane, and Claire Stuart, and Catherine Tremlett, and John Fitzgerald, and Paul Clarke
May 2007, Acta oto-laryngologica,
Ankur Sharma, and James M Leaf, and Saumya Thomas, and Christine Cane, and Claire Stuart, and Catherine Tremlett, and John Fitzgerald, and Paul Clarke
June 2001, The Journal of laryngology and otology,
Ankur Sharma, and James M Leaf, and Saumya Thomas, and Christine Cane, and Claire Stuart, and Catherine Tremlett, and John Fitzgerald, and Paul Clarke
September 1995, Journal of the American Academy of Audiology,
Ankur Sharma, and James M Leaf, and Saumya Thomas, and Christine Cane, and Claire Stuart, and Catherine Tremlett, and John Fitzgerald, and Paul Clarke
August 2022, Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India,
Ankur Sharma, and James M Leaf, and Saumya Thomas, and Christine Cane, and Claire Stuart, and Catherine Tremlett, and John Fitzgerald, and Paul Clarke
September 1980, The Laryngoscope,
Ankur Sharma, and James M Leaf, and Saumya Thomas, and Christine Cane, and Claire Stuart, and Catherine Tremlett, and John Fitzgerald, and Paul Clarke
September 1991, Developmental medicine and child neurology,
Copied contents to your clipboard!