Biomaterial Database

Graves' disease with thyrotoxicosis following subacute thyroiditis. 1987

L Wartofsky, and M Schaaf

Department of Medicine, Walter Reed Army Medical Center, Washington, D.C. 20307.

Two patients are described who manifested the sequential occurrence of Graves' disease and subacute thyroiditis. The literature on this very unusual event is reviewed and speculation is offered on a possible mechanism linking thyroiditis to activation of Graves' disease in susceptible persons.

UI	MeSH Term	Description	Entries
D005260	Female		Females
D006111	Graves Disease	A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).	Basedow's Disease,Exophthalmic Goiter,Goiter, Exophthalmic,Graves' Disease,Basedow Disease,Hyperthyroidism, Autoimmune,Basedows Disease,Disease, Basedow,Disease, Basedow's,Disease, Graves,Disease, Graves',Exophthalmic Goiters,Goiters, Exophthalmic
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D013968	Thyroiditis, Subacute	Spontaneously remitting inflammatory condition of the THYROID GLAND, characterized by FEVER; MUSCLE WEAKNESS; SORE THROAT; severe thyroid PAIN; and an enlarged damaged gland containing GIANT CELLS. The disease frequently follows a viral infection.	De Quervain Thyroiditis,Giant Cell Thyroiditis,Granulomatous Thyroiditis,Subacute Nonsuppurative Thyroiditis,Subacute Painful Thyroiditis,Cell Thyroiditides, Giant,Cell Thyroiditis, Giant,Giant Cell Thyroiditides,Granulomatous Thyroiditides,Nonsuppurative Thyroiditides, Subacute,Nonsuppurative Thyroiditis, Subacute,Painful Thyroiditides, Subacute,Painful Thyroiditis, Subacute,Subacute Nonsuppurative Thyroiditides,Subacute Painful Thyroiditides,Subacute Thyroiditides,Subacute Thyroiditis,Thyroiditides, Giant Cell,Thyroiditides, Granulomatous,Thyroiditides, Subacute,Thyroiditides, Subacute Nonsuppurative,Thyroiditides, Subacute Painful,Thyroiditis, De Quervain,Thyroiditis, Giant Cell,Thyroiditis, Granulomatous,Thyroiditis, Subacute Nonsuppurative,Thyroiditis, Subacute Painful
D013971	Thyrotoxicosis	A hypermetabolic syndrome caused by excess THYROID HORMONES which may come from endogenous or exogenous sources. The endogenous source of hormone may be thyroid HYPERPLASIA; THYROID NEOPLASMS; or hormone-producing extrathyroidal tissue. Thyrotoxicosis is characterized by NERVOUSNESS; TACHYCARDIA; FATIGUE; WEIGHT LOSS; heat intolerance; and excessive SWEATING.	Thyrotoxicoses