Biomaterial Database

N-nitrosamines and nitrosatable compounds in rubber nipples, pacifiers and other rubber and plastic commodities. 1987

G Ellen, and E T Sahertian

National Institute of Public Health and Environmental Hygiene, Bilthoven, The Netherlands.

In 1983 and 1985, rubber teats and pacifiers from the Dutch market were analysed for N-nitrosamines (NA) and nitrosatable compounds (NC) by extraction with an artificial saliva test solution (24 h, 40 degrees C). NC were determined as NA (gas chromatography-thermal energy analysis) after nitrosation. In 1983, the total content of NA and NC varied from 4-40 micrograms/kg and 50-3700 micrograms/kg, respectively (18 samples). In 1985, NA and NC varied from 3-94 micrograms/kg and 26-5100 micrograms/kg, respectively (20 samples). According to Dutch legislation, teats may contain no more than 1 microgram/kg and 20 microgram/kg NA and NC. Of other rubber and plastic commodities analysed, balloons contained levels of up to 120 micrograms/kg and 2800 micrograms/kg NA and NC.

UI	MeSH Term	Description	Entries
D007225	Infant Food	Food processed and manufactured for the nutritional health of children in their first year of life.	Food, Infant,Foods, Infant,Infant Foods
D009602	Nitrosamines	A class of compounds that contain a -NH2 and a -NO radical. Many members of this group have carcinogenic and mutagenic properties.	Nitrosamine
D009603	Nitroso Compounds	Organic compounds containing the nitroso (-N	Compounds, Nitroso
D003297	Cooking and Eating Utensils	Tools used in COOKING or EATING such as cutlery, pots, pans, and dishes.	Eating Utensils,Cooking Utensils,Cooking Utensil,Eating Utensil,Utensil, Cooking,Utensil, Eating,Utensils, Cooking,Utensils, Eating
D012408	Rubber	A high-molecular-weight polymeric elastomer derived from the milk juice (LATEX) of HEVEA brasiliensis and other trees and plants. It is a substance that can be stretched at room temperature to at least twice its original length and after releasing the stress, retract rapidly, and recover its original dimensions fully.	Latex Rubber,Elastica,India Rubber,Natural Rubber,Plant Rubber,Vulcanite,Natural Rubbers,Plant Rubbers,Rubber, Natural,Rubber, Plant,Rubbers, Natural,Rubbers, Plant
D012463	Saliva	The clear, viscous fluid secreted by the SALIVARY GLANDS and mucous glands of the mouth. It contains MUCINS, water, organic salts, and ptylin.	Salivas