N-nitrosamines and nitrosatable compounds in rubber nipples and pacifiers. 1983

B G Osterdahl

Rubber nipples and pacifiers were analysed for volatile N-nitrosamines using gas chromatography-thermal energy analysis after extraction with 'artificial saliva'. All of the 17 samples tested were found to contain at least two of the following: N-nitrosodimethylamine, N-nitrosodiethylamine, N-nitrosodibutylamine and N-nitrosopiperidine. Total volatile N-nitrosamine levels up to 19.7 micrograms/kg rubber were found, with a mean content of 7.3 micrograms/kg. Nitrosatable compounds, measured as N-nitrosamines after nitrosation, were detected in 15 of the 17 samples to total levels up to 13.7 mg/kg, the mean being 5.0 mg/kg.

UI MeSH Term Description Entries
D007223 Infant A child between 1 and 23 months of age. Infants
D007224 Infant Care Care of infants in the home or institution.
D009602 Nitrosamines A class of compounds that contain a -NH2 and a -NO radical. Many members of this group have carcinogenic and mutagenic properties. Nitrosamine
D009603 Nitroso Compounds Organic compounds containing the nitroso (-N Compounds, Nitroso
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012408 Rubber A high-molecular-weight polymeric elastomer derived from the milk juice (LATEX) of HEVEA brasiliensis and other trees and plants. It is a substance that can be stretched at room temperature to at least twice its original length and after releasing the stress, retract rapidly, and recover its original dimensions fully. Latex Rubber,Elastica,India Rubber,Natural Rubber,Plant Rubber,Vulcanite,Natural Rubbers,Plant Rubbers,Rubber, Natural,Rubber, Plant,Rubbers, Natural,Rubbers, Plant
D013548 Sweden Country in northern Europe, bordering the Baltic Sea, between Finland and Norway. The capital is Stockholm.

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