Effect of adding nano-materials on the properties of hydroxypropyl methylcellulose (HPMC) edible films. 2023

El-Sayed Khater, and Adel Bahnasawy, and Basma Abu Gabal, and Wael Abbas, and Osama Morsy
Agricultural and Biosystems Engineering Department, Faculty of Agriculture, Benha University, P.O. Box 13736, Moshtohor, Toukh, Kalubia, Egypt. alsayed.khater@fagr.bu.edu.eg.

The bio-composite films based on Hydroxypropyl methylcellulose (HPMC) reinforced with silver nanoparticles (AgNPs) and Titanium oxide nanoparticles (TiO2-NPs) were developed. Some physical and mechanical properties: Tensile strength (TS), elongation (E), Young's elastic modulus (EM), water vapor permeability (WVP) and transparency were determined. Antibacterial properties of these films were also studied. The tensile strength values of HPMC film reinforced with Ag NPs and TiO2-NPs and HPMC without nanoparticles were 39.24, 143.87 and 157.92 MPa, respectively. Elongation of the HMPC film was less than the HPMC film reinforced with AgNPs and TiO2-NPs, the results were 2, 35 and 42%, respectively. Additionally, Young's elastic modulus of HMPC film was determined to be 19.62 MPa and the HPMC film reinforced with AgNPs and TiO2-NPs were 4.11 and 3.76 MPa, respectively. The values of WVP of HMPC film was higher than the HMPC film reinforced with AgNPs and TiO2-NPs, where they were 0.5076 × 10-3, 0.4596 × 10-3 and 0.4504 × 10-3 (g/msPa), respectively. Nano-composite films demonstrated strong antibacterial activity against tested pathogen bacteria in the contact surface zone. The antibacterial activites of AgNPs (~ 10 nm) at 80 ppm were more active than 20 and 40 ppm against foodborne pathogen i.e. Bacillus cereus and Escherichia coli, the inhibition zone diameters were 9 and 10 mm, respectively. As well, TiO2-NPs (~ 50 nm) at 80 ppm were more active than 20 and 40 ppm against B. cereus and Salmonella Typhimurium, the inhibition zone diameters were11 and 10 mm, respectively.

UI MeSH Term Description Entries
D008747 Methylcellulose Methylester of cellulose. Methylcellulose is used as an emulsifying and suspending agent in cosmetics, pharmaceutics and the chemical industry. It is used therapeutically as a bulk laxative. BFL,Celevac,Cellothyl,Cellulone,Citrucel,Cologel,Dacryolarmes,Methocel,Methyl Cellulose,Muciplasma,Cellulose, Methyl
D010539 Permeability Property of membranes and other structures to permit passage of light, heat, gases, liquids, metabolites, and mineral ions. Permeabilities
D000080122 Edible Films Packaging materials that can be directly consumed. They provide barrier and protection, while enhancing quality and safety of food products. (Bourtoom, 2008). Edible Coating,Edible Food Packaging Materials,Edible Packaging,Coating, Edible,Coatings, Edible,Edible Coatings,Edible Film,Edible Packagings,Film, Edible,Films, Edible,Packaging, Edible,Packagings, Edible
D000900 Anti-Bacterial Agents Substances that inhibit the growth or reproduction of BACTERIA. Anti-Bacterial Agent,Anti-Bacterial Compound,Anti-Mycobacterial Agent,Antibacterial Agent,Antibiotics,Antimycobacterial Agent,Bacteriocidal Agent,Bacteriocide,Anti-Bacterial Compounds,Anti-Mycobacterial Agents,Antibacterial Agents,Antibiotic,Antimycobacterial Agents,Bacteriocidal Agents,Bacteriocides,Agent, Anti-Bacterial,Agent, Anti-Mycobacterial,Agent, Antibacterial,Agent, Antimycobacterial,Agent, Bacteriocidal,Agents, Anti-Bacterial,Agents, Anti-Mycobacterial,Agents, Antibacterial,Agents, Antimycobacterial,Agents, Bacteriocidal,Anti Bacterial Agent,Anti Bacterial Agents,Anti Bacterial Compound,Anti Bacterial Compounds,Anti Mycobacterial Agent,Anti Mycobacterial Agents,Compound, Anti-Bacterial,Compounds, Anti-Bacterial
D012834 Silver An element with the atomic symbol Ag, atomic number 47, and atomic weight 107.87. It is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. Long-continued use of silver salts can lead to a form of poisoning known as ARGYRIA.
D013718 Tensile Strength The maximum stress a material subjected to a stretching load can withstand without tearing. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed, p2001) Strength, Tensile,Strengths, Tensile,Tensile Strengths
D053768 Metal Nanoparticles Nanoparticles produced from metals whose uses include biosensors, optics, and catalysts. In biomedical applications the particles frequently involve the noble metals, especially gold and silver. Metal Nanocrystals,Metallic Nanocrystals,Metallic Nanoparticles,Metal Nanocrystal,Metal Nanoparticle,Metallic Nanocrystal,Metallic Nanoparticle,Nanocrystal, Metal,Nanocrystal, Metallic,Nanocrystals, Metal,Nanocrystals, Metallic,Nanoparticle, Metal,Nanoparticle, Metallic,Nanoparticles, Metal,Nanoparticles, Metallic
D065347 Hypromellose Derivatives Polymeric compounds that contain repeating units of hydroxypropyl methylcellulose. The properties of hypromellose polymers can vary greatly and are defined by their molecular weight, the percentage of hydroxyl groups, the percentage of hydroxypropyl groups, and viscosity measurements. They are found a broad variety of commercial products such as FOOD ADDITIVES; EXCIPIENTS; and LUBRICANTS. HPMC 2910,HPMC-K-100 M,Hydroxypropyl Methylcellulose,Hydroxypropylmethylcellulose,Hypromellose,K-8515,K8515,MHPC Polymer,Methocel E,Methoxyhydroxypropylcellulose,Methyl Hydroxypropyl Cellulose,Methyl-hydroxypropyl-cellulose,Derivative, Hypromellose,Derivatives, Hypromellose,HPMC K 100 M,HPMCK100 M,Hypromellose Derivative,K 8515

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