Biomaterial Database

[Influence of heat-induced changes in the mechanical properties of the membrane on the filterability of human erythrocytes]. 1986

W Kucera, and W Meier, and D Lerche

The influence of heat induced changes of mechanical membrane properties of human erythrocytes on their filterability was investigated. A 10-minute incubation at 47, 48 and 48.4 degrees C, respectively, leads to an increase of elastic membrane shear modulus (up to 130%, 240%, 260%) and membrane viscosity (up to 220%, 380%, 480%). In comparison to these effects the filterability determined by cellulose filters was diminished relatively slightly (increase of filterability index up to 110%, 130%, 170%), with the mean erythrocyte volume remaining unchanged. Taking into account former investigations it is concluded that the used filtration technique is less sensitive with respect to changes of the elastic and viscous membrane properties compared with changes of cytoplasmic viscosity of the cells.

UI	MeSH Term	Description	Entries
D001809	Blood Viscosity	The internal resistance of the BLOOD to shear forces. The in vitro measure of whole blood viscosity is of limited clinical utility because it bears little relationship to the actual viscosity within the circulation, but an increase in the viscosity of circulating blood can contribute to morbidity in patients suffering from disorders such as SICKLE CELL ANEMIA and POLYCYTHEMIA.	Blood Viscosities,Viscosities, Blood,Viscosity, Blood
D002482	Cellulose	A polysaccharide with glucose units linked as in CELLOBIOSE. It is the chief constituent of plant fibers, cotton being the purest natural form of the substance. As a raw material, it forms the basis for many derivatives used in chromatography, ion exchange materials, explosives manufacturing, and pharmaceutical preparations.	Alphacel,Avicel,Heweten,Polyanhydroglucuronic Acid,Rayophane,Sulfite Cellulose,alpha-Cellulose,Acid, Polyanhydroglucuronic,alpha Cellulose
D004907	Erythrocyte Deformability	Ability of ERYTHROCYTES to change shape as they pass through narrow spaces, such as the microvasculature.	Erythrocyte Filterability,Deformability, Erythrocyte,Filterability, Erythrocyte
D004910	Erythrocyte Membrane	The semi-permeable outer structure of a red blood cell. It is known as a red cell 'ghost' after HEMOLYSIS.	Erythrocyte Ghost,Red Cell Cytoskeleton,Red Cell Ghost,Erythrocyte Cytoskeleton,Cytoskeleton, Erythrocyte,Cytoskeleton, Red Cell,Erythrocyte Cytoskeletons,Erythrocyte Ghosts,Erythrocyte Membranes,Ghost, Erythrocyte,Ghost, Red Cell,Membrane, Erythrocyte,Red Cell Cytoskeletons,Red Cell Ghosts
D004911	Erythrocyte Volume	Volume of circulating ERYTHROCYTES . It is usually measured by RADIOISOTOPE DILUTION TECHNIQUE.	Red Cell Mass,Erythrocyte Volumes,Mass, Red Cell,Masses, Red Cell,Red Cell Masses,Volume, Erythrocyte,Volumes, Erythrocyte
D006358	Hot Temperature	Presence of warmth or heat or a temperature notably higher than an accustomed norm.	Heat,Hot Temperatures,Temperature, Hot,Temperatures, Hot
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor