-transparent.png){kind=logo}
Full-field electroretinograms (ERGs) were recorded between the ages of 4 and 34 months from 8 miniature French poodles with inherited progressive rod-cone degeneration (PRCD) and from 11 normal miniature poodles. Three stages of retinal function were observed in the affected dogs, although the ages of transition from one stage to the next were variable among dogs. Rod and cone ERGs were normal in amplitude in the first stage, rod ERGs were reduced in amplitude and cone ERGs were normal in the second, and rod ERGs were extremely reduced in amplitude or nondetectable and cone ERGs were reduced in amplitude in the third. On average, these poodles with PRCD lost 7.2% of remaining rod amplitude per month and 2% of remaining cone amplitude per month. Affected poodles had normal rod and cone b-wave implicit times over all three stages, in contrast to humans with the early stages of progressive forms of retinitis pigmentosa who have delayed rod and/or cone b-wave implicit times.
M A Sandberg, and
B S Pawlyk, and
E L Berson
November 1982,
Investigative ophthalmology & visual science,
M A Sandberg, and
B S Pawlyk, and
E L Berson
January 1987,
Progress in clinical and biological research,
M A Sandberg, and
B S Pawlyk, and
E L Berson
January 1990,
Experimental eye research,
M A Sandberg, and
B S Pawlyk, and
E L Berson
January 1989,
Progress in clinical and biological research,
M A Sandberg, and
B S Pawlyk, and
E L Berson
June 1992,
Experimental eye research,
M A Sandberg, and
B S Pawlyk, and
E L Berson
March 1991,
Experimental eye research,
M A Sandberg, and
B S Pawlyk, and
E L Berson
July 1968,
Archives of ophthalmology (Chicago, Ill. : 1960),
M A Sandberg, and
B S Pawlyk, and
E L Berson
March 2016,
The Journal of veterinary medical science,
M A Sandberg, and
B S Pawlyk, and
E L Berson
March 1990,
American journal of medical genetics,
M A Sandberg, and
B S Pawlyk, and
E L Berson
January 1996,
Acta ophthalmologica Scandinavica. Supplement,
