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The reactivity of B73.1 monoclonal antibody was evaluated on unseparated and on T cell-depleted and T cell-enriched fractions of both cord blood lymphocytes (CBL) and adult peripheral blood lymphocytes (a-PBL). The reactivity of this monoclonal antibody with the E-, OKT3-, OKT8+, HNK-1- subset of CBL, previously demonstrated to have NK activity, was also studied. The data show that B73.1+ cells were present in similar percentages in CBL and a-PBL while HNK-1+ cells were very low in CBL. In addition the B73.1 monoclonal antibody reacted with about 50% of the E-, OKT3-, OKT8+, HNK-1- CBL and within this subset the majority of the B73.1+ cells were PNA-. These data support the hypothesis that part of this neonatal subpopulation, belongs to the NK cell lineage. Moreover the results obtained by double-labelling with B73.1 monoclonal antibody and PNA suggest that the E-, OKT3-, OKT8+, HNK-1- CBL include either different subsets or various differentiation stages of the same subset.
D Montagna, and
P Ferremi, and
C Alberini, and
F A Porta, and
M de Amici, and
G C Astaldi-Ricotti, and
R Maccario, and
A G Ugazio
July 1984,
Clinical and experimental immunology,
D Montagna, and
P Ferremi, and
C Alberini, and
F A Porta, and
M de Amici, and
G C Astaldi-Ricotti, and
R Maccario, and
A G Ugazio
January 1985,
Thymus,
D Montagna, and
P Ferremi, and
C Alberini, and
F A Porta, and
M de Amici, and
G C Astaldi-Ricotti, and
R Maccario, and
A G Ugazio
April 1984,
Cellular immunology,
D Montagna, and
P Ferremi, and
C Alberini, and
F A Porta, and
M de Amici, and
G C Astaldi-Ricotti, and
R Maccario, and
A G Ugazio
January 1986,
Thymus,
D Montagna, and
P Ferremi, and
C Alberini, and
F A Porta, and
M de Amici, and
G C Astaldi-Ricotti, and
R Maccario, and
A G Ugazio
January 1991,
Biology of the neonate,
D Montagna, and
P Ferremi, and
C Alberini, and
F A Porta, and
M de Amici, and
G C Astaldi-Ricotti, and
R Maccario, and
A G Ugazio
December 1983,
Gastroenterology,
D Montagna, and
P Ferremi, and
C Alberini, and
F A Porta, and
M de Amici, and
G C Astaldi-Ricotti, and
R Maccario, and
A G Ugazio
November 1973,
Clinical and experimental immunology,
D Montagna, and
P Ferremi, and
C Alberini, and
F A Porta, and
M de Amici, and
G C Astaldi-Ricotti, and
R Maccario, and
A G Ugazio
November 1982,
Cellular immunology,
D Montagna, and
P Ferremi, and
C Alberini, and
F A Porta, and
M de Amici, and
G C Astaldi-Ricotti, and
R Maccario, and
A G Ugazio
June 1984,
Journal of neuroimmunology,
D Montagna, and
P Ferremi, and
C Alberini, and
F A Porta, and
M de Amici, and
G C Astaldi-Ricotti, and
R Maccario, and
A G Ugazio
March 1983,
Journal of immunology (Baltimore, Md. : 1950),
