Biomaterial Database

Effect of cadmium on lipid composition of the weanling rat brain. 1986

S Gulati, and K D Gill, and R Nath

The effect of early postnatal cadmium exposure (cadmium injected at dose levels of 1 and 2 mg cadmium/kg body weight on 3rd, 10th and 17th day after birth) on various lipid fractions of the weanling rat brain was studied. The results suggest that cadmium treatment (a dose of only 2 mg Cd/kg) results in an appreciable decrease in myelin-specific lipids like nonesterified cholesterol, ethanolamine-containing lipids, cerebrosides and sulfatides leading to hypomyelination. The lower dose of cadmium (1 mg Cd/kg) did not have any significant effect.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D009929	Organ Size	The measurement of an organ in volume, mass, or heaviness.	Organ Volume,Organ Weight,Size, Organ,Weight, Organ
D010743	Phospholipids	Lipids containing one or more phosphate groups, particularly those derived from either glycerol (phosphoglycerides see GLYCEROPHOSPHOLIPIDS) or sphingosine (SPHINGOLIPIDS). They are polar lipids that are of great importance for the structure and function of cell membranes and are the most abundant of membrane lipids, although not stored in large amounts in the system.	Phosphatides,Phospholipid
D011247	Pregnancy	The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	Gestation,Pregnancies
D001835	Body Weight	The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.	Body Weights,Weight, Body,Weights, Body
D001923	Brain Chemistry	Changes in the amounts of various chemicals (neurotransmitters, receptors, enzymes, and other metabolites) specific to the area of the central nervous system contained within the head. These are monitored over time, during sensory stimulation, or under different disease states.	Chemistry, Brain,Brain Chemistries,Chemistries, Brain
D002104	Cadmium	An element with atomic symbol Cd, atomic number 48, and atomic weight 112.41. It is a metal and ingestion will lead to CADMIUM POISONING.
D002784	Cholesterol	The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.	Epicholesterol
D003300	Copper	A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.	Copper-63,Copper 63
D005260	Female		Females