-transparent.png){kind=logo}
The level of muscarinic receptors on lymphocytes from rheumatoid arthritis (RA) patients in comparison with healthy individuals was determined by the binding studies of a specific muscarinic ligand [3H]-QNB in the presence of the competitive antagonist atropine. The response to phytohaemagglutinin and the influence of acetylcholine on this process in patients' lymphocytes was also studied. We have found direct correlation among PHA stimulation indices, the level of muscarinic receptors, and the influence of acetylcholine on PHA stimulation indices. Differences in these parameters occurring in systemic forms of RA as compared to other RA patients are also described and their possible mechanism discussed. The influence of cholinergic stimulation on the reactivity of lymphocytes after PHA in different forms of RA could depend on the number of muscarinic receptors present on the lymphocyte surface, as well as on the activity of soluble factors, which could modulate the functional state of the receptors.
H Laskowska-Bozek, and
E Grabczewska, and
W Maśliński, and
J Ryzewski, and
A Filipowicz-Sosnowska, and
M Sadowska-Wróblewska
July 1994,
The Journal of rheumatology,
H Laskowska-Bozek, and
E Grabczewska, and
W Maśliński, and
J Ryzewski, and
A Filipowicz-Sosnowska, and
M Sadowska-Wróblewska
December 1987,
Biological psychiatry,
H Laskowska-Bozek, and
E Grabczewska, and
W Maśliński, and
J Ryzewski, and
A Filipowicz-Sosnowska, and
M Sadowska-Wróblewska
June 1997,
Revista de neurologia,
H Laskowska-Bozek, and
E Grabczewska, and
W Maśliński, and
J Ryzewski, and
A Filipowicz-Sosnowska, and
M Sadowska-Wróblewska
May 1997,
Plant molecular biology,
H Laskowska-Bozek, and
E Grabczewska, and
W Maśliński, and
J Ryzewski, and
A Filipowicz-Sosnowska, and
M Sadowska-Wróblewska
June 1978,
Proceedings of the National Academy of Sciences of the United States of America,
H Laskowska-Bozek, and
E Grabczewska, and
W Maśliński, and
J Ryzewski, and
A Filipowicz-Sosnowska, and
M Sadowska-Wróblewska
January 1988,
Immunopharmacology,
H Laskowska-Bozek, and
E Grabczewska, and
W Maśliński, and
J Ryzewski, and
A Filipowicz-Sosnowska, and
M Sadowska-Wróblewska
January 1983,
Research communications in chemical pathology and pharmacology,
H Laskowska-Bozek, and
E Grabczewska, and
W Maśliński, and
J Ryzewski, and
A Filipowicz-Sosnowska, and
M Sadowska-Wróblewska
March 1978,
Nature,
H Laskowska-Bozek, and
E Grabczewska, and
W Maśliński, and
J Ryzewski, and
A Filipowicz-Sosnowska, and
M Sadowska-Wróblewska
July 2009,
Ginecologia y obstetricia de Mexico,
H Laskowska-Bozek, and
E Grabczewska, and
W Maśliński, and
J Ryzewski, and
A Filipowicz-Sosnowska, and
M Sadowska-Wróblewska
September 1988,
Arthritis and rheumatism,
