-transparent.png){kind=logo}
Safety evaluation of synthesised DNA oligonucleotides as a food additive. 2023
, and
Maged Younes, and
Gabriele Aquilina, and
Gisela Degen, and
Karl-Heinz Engel, and
Paul Fowler, and
Maria Jose Frutos Fernandez, and
Peter Fürst, and
Ursula Gundert-Remy, and
Rainer Gürtler, and
Trine Husøy, and
Melania Manco, and
Wim Mennes, and
Sabina Passamonti, and
Peter Moldeus, and
Romina Shah, and
Ine Waalkens-Berendsen, and
Matthew Wright, and
José Manuel Barat Baviera, and
David Gott, and
Lieve Herman, and
Jean-Charles Leblanc, and
Detlef Wölfle, and
Jaime Aguilera Entrena, and
Laura Ruggeri, and
Camilla Smeraldi, and
Alexandra Tard, and
Laurence Castle
The EFSA Panel on Food Additives and Flavourings (FAF) was requested to evaluate the safety of synthesised DNA oligonucleotides as a new food additive, in accordance with Regulation (EC) No 1331/2008. Considering that the additional information requested by the Panel during the risk assessment was not provided by the applicant, the assessment was concluded on the basis of the sole information available in the application. The proposed food additive consists of purified synthetic DNA sequences intended to be used for traceability purposes, alone or combined with carriers. Information provided by the applicant on the identity, characterisation and production process of the proposed food additive was considered insufficient. The Panel considered that the product specifications as proposed by the applicant do not adequately define and characterise the proposed food additive. The applicant proposed for the food additive the maximum use levels of 0.001 mg/kg for a variety of food categories. The food additive was also proposed as a Group I additive at a specific maximum level of quantum satis. The applicant did not provide exposure estimates according to the EFSA ANS Panel guidance (2012). No biological or toxicological data were provided by the applicant for the proposed food additive. Considering the inadequate information available and the uncertainty introduced by the proposal at quantum satis, along with the insufficient specifications, the Panel could not conclude on the safety of the food additive as proposed and described by the applicant.
| UI | MeSH Term | Description | Entries |
|---|
Related Publications
, and
Maged Younes, and
Gabriele Aquilina, and
Gisela Degen, and
Karl-Heinz Engel, and
Paul Fowler, and
Maria Jose Frutos Fernandez, and
Peter Fürst, and
Ursula Gundert-Remy, and
Rainer Gürtler, and
Trine Husøy, and
Melania Manco, and
Wim Mennes, and
Sabina Passamonti, and
Peter Moldeus, and
Romina Shah, and
Ine Waalkens-Berendsen, and
Matthew Wright, and
José Manuel Barat Baviera, and
David Gott, and
Lieve Herman, and
Jean-Charles Leblanc, and
Detlef Wölfle, and
Jaime Aguilera Entrena, and
Laura Ruggeri, and
Camilla Smeraldi, and
Alexandra Tard, and
Laurence Castle
December 2023,
EFSA journal. European Food Safety Authority,
, and
Maged Younes, and
Gabriele Aquilina, and
Gisela Degen, and
Karl-Heinz Engel, and
Paul Fowler, and
Maria Jose Frutos Fernandez, and
Peter Fürst, and
Ursula Gundert-Remy, and
Rainer Gürtler, and
Trine Husøy, and
Melania Manco, and
Wim Mennes, and
Sabina Passamonti, and
Peter Moldeus, and
Romina Shah, and
Ine Waalkens-Berendsen, and
Matthew Wright, and
José Manuel Barat Baviera, and
David Gott, and
Lieve Herman, and
Jean-Charles Leblanc, and
Detlef Wölfle, and
Jaime Aguilera Entrena, and
Laura Ruggeri, and
Camilla Smeraldi, and
Alexandra Tard, and
Laurence Castle
July 2022,
EFSA journal. European Food Safety Authority,
, and
Maged Younes, and
Gabriele Aquilina, and
Gisela Degen, and
Karl-Heinz Engel, and
Paul Fowler, and
Maria Jose Frutos Fernandez, and
Peter Fürst, and
Ursula Gundert-Remy, and
Rainer Gürtler, and
Trine Husøy, and
Melania Manco, and
Wim Mennes, and
Sabina Passamonti, and
Peter Moldeus, and
Romina Shah, and
Ine Waalkens-Berendsen, and
Matthew Wright, and
José Manuel Barat Baviera, and
David Gott, and
Lieve Herman, and
Jean-Charles Leblanc, and
Detlef Wölfle, and
Jaime Aguilera Entrena, and
Laura Ruggeri, and
Camilla Smeraldi, and
Alexandra Tard, and
Laurence Castle
February 2022,
EFSA journal. European Food Safety Authority,
, and
Maged Younes, and
Gabriele Aquilina, and
Gisela Degen, and
Karl-Heinz Engel, and
Paul Fowler, and
Maria Jose Frutos Fernandez, and
Peter Fürst, and
Ursula Gundert-Remy, and
Rainer Gürtler, and
Trine Husøy, and
Melania Manco, and
Wim Mennes, and
Sabina Passamonti, and
Peter Moldeus, and
Romina Shah, and
Ine Waalkens-Berendsen, and
Matthew Wright, and
José Manuel Barat Baviera, and
David Gott, and
Lieve Herman, and
Jean-Charles Leblanc, and
Detlef Wölfle, and
Jaime Aguilera Entrena, and
Laura Ruggeri, and
Camilla Smeraldi, and
Alexandra Tard, and
Laurence Castle
August 2021,
EFSA journal. European Food Safety Authority,
, and
Maged Younes, and
Gabriele Aquilina, and
Gisela Degen, and
Karl-Heinz Engel, and
Paul Fowler, and
Maria Jose Frutos Fernandez, and
Peter Fürst, and
Ursula Gundert-Remy, and
Rainer Gürtler, and
Trine Husøy, and
Melania Manco, and
Wim Mennes, and
Sabina Passamonti, and
Peter Moldeus, and
Romina Shah, and
Ine Waalkens-Berendsen, and
Matthew Wright, and
José Manuel Barat Baviera, and
David Gott, and
Lieve Herman, and
Jean-Charles Leblanc, and
Detlef Wölfle, and
Jaime Aguilera Entrena, and
Laura Ruggeri, and
Camilla Smeraldi, and
Alexandra Tard, and
Laurence Castle
May 2021,
EFSA journal. European Food Safety Authority,
, and
Maged Younes, and
Gabriele Aquilina, and
Gisela Degen, and
Karl-Heinz Engel, and
Paul Fowler, and
Maria Jose Frutos Fernandez, and
Peter Fürst, and
Ursula Gundert-Remy, and
Rainer Gürtler, and
Trine Husøy, and
Melania Manco, and
Wim Mennes, and
Sabina Passamonti, and
Peter Moldeus, and
Romina Shah, and
Ine Waalkens-Berendsen, and
Matthew Wright, and
José Manuel Barat Baviera, and
David Gott, and
Lieve Herman, and
Jean-Charles Leblanc, and
Detlef Wölfle, and
Jaime Aguilera Entrena, and
Laura Ruggeri, and
Camilla Smeraldi, and
Alexandra Tard, and
Laurence Castle
February 1966,
Food and cosmetics toxicology,
, and
Maged Younes, and
Gabriele Aquilina, and
Gisela Degen, and
Karl-Heinz Engel, and
Paul Fowler, and
Maria Jose Frutos Fernandez, and
Peter Fürst, and
Ursula Gundert-Remy, and
Rainer Gürtler, and
Trine Husøy, and
Melania Manco, and
Wim Mennes, and
Sabina Passamonti, and
Peter Moldeus, and
Romina Shah, and
Ine Waalkens-Berendsen, and
Matthew Wright, and
José Manuel Barat Baviera, and
David Gott, and
Lieve Herman, and
Jean-Charles Leblanc, and
Detlef Wölfle, and
Jaime Aguilera Entrena, and
Laura Ruggeri, and
Camilla Smeraldi, and
Alexandra Tard, and
Laurence Castle
January 2021,
EFSA journal. European Food Safety Authority,
, and
Maged Younes, and
Gabriele Aquilina, and
Gisela Degen, and
Karl-Heinz Engel, and
Paul Fowler, and
Maria Jose Frutos Fernandez, and
Peter Fürst, and
Ursula Gundert-Remy, and
Rainer Gürtler, and
Trine Husøy, and
Melania Manco, and
Wim Mennes, and
Sabina Passamonti, and
Peter Moldeus, and
Romina Shah, and
Ine Waalkens-Berendsen, and
Matthew Wright, and
José Manuel Barat Baviera, and
David Gott, and
Lieve Herman, and
Jean-Charles Leblanc, and
Detlef Wölfle, and
Jaime Aguilera Entrena, and
Laura Ruggeri, and
Camilla Smeraldi, and
Alexandra Tard, and
Laurence Castle
April 2017,
EFSA journal. European Food Safety Authority,
, and
Maged Younes, and
Gabriele Aquilina, and
Gisela Degen, and
Karl-Heinz Engel, and
Paul Fowler, and
Maria Jose Frutos Fernandez, and
Peter Fürst, and
Ursula Gundert-Remy, and
Rainer Gürtler, and
Trine Husøy, and
Melania Manco, and
Wim Mennes, and
Sabina Passamonti, and
Peter Moldeus, and
Romina Shah, and
Ine Waalkens-Berendsen, and
Matthew Wright, and
José Manuel Barat Baviera, and
David Gott, and
Lieve Herman, and
Jean-Charles Leblanc, and
Detlef Wölfle, and
Jaime Aguilera Entrena, and
Laura Ruggeri, and
Camilla Smeraldi, and
Alexandra Tard, and
Laurence Castle
June 2017,
EFSA journal. European Food Safety Authority,
, and
Maged Younes, and
Gabriele Aquilina, and
Gisela Degen, and
Karl-Heinz Engel, and
Paul Fowler, and
Maria Jose Frutos Fernandez, and
Peter Fürst, and
Ursula Gundert-Remy, and
Rainer Gürtler, and
Trine Husøy, and
Melania Manco, and
Wim Mennes, and
Sabina Passamonti, and
Peter Moldeus, and
Romina Shah, and
Ine Waalkens-Berendsen, and
Matthew Wright, and
José Manuel Barat Baviera, and
David Gott, and
Lieve Herman, and
Jean-Charles Leblanc, and
Detlef Wölfle, and
Jaime Aguilera Entrena, and
Laura Ruggeri, and
Camilla Smeraldi, and
Alexandra Tard, and
Laurence Castle
March 2017,
EFSA journal. European Food Safety Authority,
