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We have compared a few parameters of magnesium metabolism in spontaneously hypertensive (SHR) and Wistar Kyoto rats (WKY). The results show a decrease of plasma magnesium and urinary magnesium. There is no difference in fecal magnesium and in balance of magnesium. These results have raised a question as to the importance of changes in magnesium metabolism in the mechanism of hypertension.
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