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We evaluated a new Seralyzer Aris reagent strip test (Ames Div., Miles Labs.) for the determination of theophylline in human serum. The method is based on the monoclonal enzyme immunoassay with dry reagent chemistry. The analysis is rapid and simple to perform: results are available only 5-10 min after receipt of the sample. Intra-assay precision (CV) was 2.2-3.3% (n = 15) for theophylline concentrations of 5-25 mg/L; interassay CV was 5.9% (n = 19) at 15 mg/L. The results (y) agreed well with those by liquid chromatography (x): r = 0.949 (p less than 0.001), and y = 0.967x + 0.214. We conclude the method is useful for rapid evaluation of theophylline concentrations in asthmatic patients.
R Lindberg, and
K Ivaska, and
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T Vanto
January 1987,
Clinical chemistry,
R Lindberg, and
K Ivaska, and
K Irjala, and
T Vanto
February 1986,
Clinical chemistry,
R Lindberg, and
K Ivaska, and
K Irjala, and
T Vanto
February 1985,
Clinical chemistry,
R Lindberg, and
K Ivaska, and
K Irjala, and
T Vanto
November 1986,
Clinical chemistry,
R Lindberg, and
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K Irjala, and
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November 1985,
Clinical chemistry,
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August 1986,
Annals of allergy,
R Lindberg, and
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April 1986,
Chest,
R Lindberg, and
K Ivaska, and
K Irjala, and
T Vanto
May 1985,
Clinical chemistry,
R Lindberg, and
K Ivaska, and
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T Vanto
January 1985,
The Diabetes educator,
R Lindberg, and
K Ivaska, and
K Irjala, and
T Vanto
February 1988,
Clinical chemistry,
