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In view of theoretical concern that psoralen ultraviolet A radiation (PUVA) therapy might induce a systemic lupus erythematosus-like syndrome, we studied serum antinuclear antibodies (ANAs) in patients with psoriasis who received PUVA and are participating in a five-year prospective study. At 14 centers, 1,023 patients had two or more ANA determinations. When first and last tests were compared, the incidence of positive tests for ANAs was not significantly different (P greater than .2). In addition, there was no apparent relationship between the frequency of PUVA treatments and the probability of a positive test. Over a two-year period, there is no evidence to indicate that PUVA therapy for psoriasis has resulted in a significantly higher number of positive tests for ANAs within our population.
R S Stern, and
W L Morison, and
L A Thibodeau, and
R A Kleinerman, and
J A Parrish, and
D E Geer, and
T B Fitzpatrick
August 1981,
Archives of dermatology,
R S Stern, and
W L Morison, and
L A Thibodeau, and
R A Kleinerman, and
J A Parrish, and
D E Geer, and
T B Fitzpatrick
September 1980,
Journal of the American Academy of Dermatology,
R S Stern, and
W L Morison, and
L A Thibodeau, and
R A Kleinerman, and
J A Parrish, and
D E Geer, and
T B Fitzpatrick
January 1981,
Acta dermato-venereologica,
R S Stern, and
W L Morison, and
L A Thibodeau, and
R A Kleinerman, and
J A Parrish, and
D E Geer, and
T B Fitzpatrick
July 1981,
American journal of hospital pharmacy,
R S Stern, and
W L Morison, and
L A Thibodeau, and
R A Kleinerman, and
J A Parrish, and
D E Geer, and
T B Fitzpatrick
September 1980,
International journal of dermatology,
R S Stern, and
W L Morison, and
L A Thibodeau, and
R A Kleinerman, and
J A Parrish, and
D E Geer, and
T B Fitzpatrick
January 1981,
The Journal of the Kentucky Medical Association,
R S Stern, and
W L Morison, and
L A Thibodeau, and
R A Kleinerman, and
J A Parrish, and
D E Geer, and
T B Fitzpatrick
December 1974,
The New England journal of medicine,
R S Stern, and
W L Morison, and
L A Thibodeau, and
R A Kleinerman, and
J A Parrish, and
D E Geer, and
T B Fitzpatrick
January 1985,
Acta dermato-venereologica,
R S Stern, and
W L Morison, and
L A Thibodeau, and
R A Kleinerman, and
J A Parrish, and
D E Geer, and
T B Fitzpatrick
July 1976,
Archives of dermatology,
R S Stern, and
W L Morison, and
L A Thibodeau, and
R A Kleinerman, and
J A Parrish, and
D E Geer, and
T B Fitzpatrick
June 1976,
The Journal of the American Osteopathic Association,
