Post-transplantation lymphocele ordinarily is an early postoperative complication that infrequently causes symptoms, which usually result from impaired renal function secondary to cortical compression or ureteral obstruction. We recently encountered a patient in whom a lymphocele developed following trauma 7 years after cadaveric transplantation. Attempts to drain the lymphocele externally resulted in massive fluid loss, which caused hypotension, hypoproteinemia and profound electrolyte imbalance. Control of the massive fluid loss was achieved by marsupialization of the lymphocele into the peritoneal cavity.