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Pertussis vaccine consisting of inactivated whole Bordetella pertussis organisms appears to induce a biphasic response on the glucose metabolism of N:NIH mice. A heat stable component assumed to be the LPS induces a transient hyperglycaemia within 6 hours after vaccination. A heat labile component assumed to be LPF, induces a hypoglycaemia and hyperinsulinaemia 2-7 days after treatment. A purified vaccine examined in this study still showed some effects on the glucose metabolism at 3-4 days after vaccination. If hypoglycaemia contributes to the neurological side effects, incidentally observed after vaccination of infants, both LPS and LPF have to be considered to be responsible for these effects.
J G Kreeftenberg, and
I van Straaten-vd Kappelle, and
D J de Wildt, and
J G Loeber
July 1983,
Infection and immunity,
J G Kreeftenberg, and
I van Straaten-vd Kappelle, and
D J de Wildt, and
J G Loeber
April 2010,
The Journal of pediatrics,
J G Kreeftenberg, and
I van Straaten-vd Kappelle, and
D J de Wildt, and
J G Loeber
October 1996,
Infection and immunity,
J G Kreeftenberg, and
I van Straaten-vd Kappelle, and
D J de Wildt, and
J G Loeber
December 1979,
The Indian journal of medical research,
J G Kreeftenberg, and
I van Straaten-vd Kappelle, and
D J de Wildt, and
J G Loeber
September 2020,
Pediatrics,
J G Kreeftenberg, and
I van Straaten-vd Kappelle, and
D J de Wildt, and
J G Loeber
February 2008,
Endocrinology,
J G Kreeftenberg, and
I van Straaten-vd Kappelle, and
D J de Wildt, and
J G Loeber
January 1988,
Diabetes care,
J G Kreeftenberg, and
I van Straaten-vd Kappelle, and
D J de Wildt, and
J G Loeber
March 1963,
British medical journal,
J G Kreeftenberg, and
I van Straaten-vd Kappelle, and
D J de Wildt, and
J G Loeber
January 1987,
Endocrinology,
J G Kreeftenberg, and
I van Straaten-vd Kappelle, and
D J de Wildt, and
J G Loeber
September 2010,
Journal of medical microbiology,
