-transparent.png){kind=logo}
The promoting effect of trisodium nitrilotriacetate monohydrate (Na3NTA X H2O) on two-stage urinary bladder carcinogenesis in F344 rats initiated with N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN) at levels of 0.01 and 0.05% was investigated. Administration of 2.0% Na3NTA X H2O significantly increased both the incidence and the number per 10 cm of basement membrane of preneoplastic lesions and papillomas of the urinary bladder in rats pretreated with 0.05% BBN. This result shows that Na3NTA X H2O has weak promoting activity in urinary bladder carcinogenesis.
Related Publications
S Fukushima, and
Y Kurata, and
S Tamano, and
K Inoue, and
N Ito
September 1985,
Japanese journal of cancer research : Gann,
S Fukushima, and
Y Kurata, and
S Tamano, and
K Inoue, and
N Ito
January 1985,
Journal of the National Cancer Institute,
S Fukushima, and
Y Kurata, and
S Tamano, and
K Inoue, and
N Ito
December 1988,
Cancer letters,
S Fukushima, and
Y Kurata, and
S Tamano, and
K Inoue, and
N Ito
November 1996,
Japanese journal of cancer research : Gann,
S Fukushima, and
Y Kurata, and
S Tamano, and
K Inoue, and
N Ito
August 1982,
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association,
S Fukushima, and
Y Kurata, and
S Tamano, and
K Inoue, and
N Ito
June 1985,
Carcinogenesis,
S Fukushima, and
Y Kurata, and
S Tamano, and
K Inoue, and
N Ito
February 1984,
Journal of the National Cancer Institute,
S Fukushima, and
Y Kurata, and
S Tamano, and
K Inoue, and
N Ito
October 1972,
Toxicology and applied pharmacology,
S Fukushima, and
Y Kurata, and
S Tamano, and
K Inoue, and
N Ito
July 1984,
Cancer letters,
S Fukushima, and
Y Kurata, and
S Tamano, and
K Inoue, and
N Ito
September 1983,
Cancer research,
