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Twenty-one patients with disseminated malignant melanoma were treated with cis-dichlorodiammine-platinum(II) (cis-DDP): ten with cis-DDP alone at a dose of 20 mg/m2 iv x 4 days every 4 weeks and 11 with cis-DDP at a dose of 15 mg/m2 iv x 4 days combined with DTIC at a dose of 200 mg/m2 iv x 5 days every 4 weeks. Two of 21 patients (10%) showed a partial response to therapy. There were no complete responses and no apparent increases in length of survival for responders compared to nonresponders. One drug-related death occurred. Otherwise, drug toxicity was acceptable and appeared to be diminished by iv hydration and prolonged administration. In this study, cis-DDP was not effective for treatment of disseminated malignant melanoma.
J E Goodnight, and
H S Moseley, and
F R Eilber, and
G Sarna, and
D L Morton
January 1979,
Cancer treatment reports,
J E Goodnight, and
H S Moseley, and
F R Eilber, and
G Sarna, and
D L Morton
March 1979,
Cancer treatment reports,
J E Goodnight, and
H S Moseley, and
F R Eilber, and
G Sarna, and
D L Morton
January 1978,
Cancer treatment reports,
J E Goodnight, and
H S Moseley, and
F R Eilber, and
G Sarna, and
D L Morton
January 1980,
Journal of cancer research and clinical oncology,
J E Goodnight, and
H S Moseley, and
F R Eilber, and
G Sarna, and
D L Morton
January 1981,
Cancer treatment reports,
J E Goodnight, and
H S Moseley, and
F R Eilber, and
G Sarna, and
D L Morton
January 2001,
Anticancer research,
J E Goodnight, and
H S Moseley, and
F R Eilber, and
G Sarna, and
D L Morton
February 1992,
American journal of clinical oncology,
J E Goodnight, and
H S Moseley, and
F R Eilber, and
G Sarna, and
D L Morton
January 1989,
Journal of cancer research and clinical oncology,
J E Goodnight, and
H S Moseley, and
F R Eilber, and
G Sarna, and
D L Morton
August 1977,
Cancer treatment reports,
J E Goodnight, and
H S Moseley, and
F R Eilber, and
G Sarna, and
D L Morton
January 1979,
Cancer treatment reports,
