Renal excretion in gull chicks: effect of parathyroid hormone and calcium loading. 1986

N B Clark, and L L Mok

Renal clearance experiments were performed on herring gull (Larus argentatus) and great black-backed gull chicks (L. marinus) to test the importance of parathyroid hormone (PTH), parathyroidectomy (PTX), and calcium loading on excretion patterns of sodium, potassium, calcium, and phosphate. PTX reduced the relative clearance of phosphate to near zero within 2 h. Conversely, PTH stimulated net secretion of phosphate within 40 min. Calcium loading caused a drop in phosphate excretion identical to that of PTX, presumably by inhibiting PTH secretion by the parathyroid glands. This also could be reversed by administration of PTH. Serum phosphate values were highest in PTX gulls and lowest in calcium-loaded gulls. The relative clearance of calcium (CCa/CIn) was elevated in calcium-loaded birds. However, CCa/CIn did not change significantly in response to either PTX or PTH in the sham-operated or PTX birds. Serum calcium values were highest in calcium-loaded gulls and lowest in PTX gulls, the reciprocal of the effects on serum phosphate.

UI MeSH Term Description Entries
D007668 Kidney Body organ that filters blood for the secretion of URINE and that regulates ion concentrations. Kidneys
D010280 Parathyroid Glands Two pairs of small oval-shaped glands located in the front and the base of the NECK and adjacent to the two lobes of THYROID GLAND. They secrete PARATHYROID HORMONE that regulates the balance of CALCIUM; PHOSPHORUS; and MAGNESIUM in the body. Gland, Parathyroid,Glands, Parathyroid,Parathyroid Gland
D010281 Parathyroid Hormone A polypeptide hormone (84 amino acid residues) secreted by the PARATHYROID GLANDS which performs the essential role of maintaining intracellular CALCIUM levels in the body. Parathyroid hormone increases intracellular calcium by promoting the release of CALCIUM from BONE, increases the intestinal absorption of calcium, increases the renal tubular reabsorption of calcium, and increases the renal excretion of phosphates. Natpara,PTH (1-84),PTH(1-34),Parathormone,Parathyrin,Parathyroid Hormone (1-34),Parathyroid Hormone (1-84),Parathyroid Hormone Peptide (1-34),Hormone, Parathyroid
D010710 Phosphates Inorganic salts of phosphoric acid. Inorganic Phosphate,Phosphates, Inorganic,Inorganic Phosphates,Orthophosphate,Phosphate,Phosphate, Inorganic
D011188 Potassium An element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.
D002118 Calcium A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. Coagulation Factor IV,Factor IV,Blood Coagulation Factor IV,Calcium-40,Calcium 40,Factor IV, Coagulation
D004231 Diuresis An increase in the excretion of URINE. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed) Diureses
D005919 Glomerular Filtration Rate The volume of water filtered out of plasma through glomerular capillary walls into Bowman's capsules per unit of time. It is considered to be equivalent to INULIN clearance. Filtration Rate, Glomerular,Filtration Rates, Glomerular,Glomerular Filtration Rates,Rate, Glomerular Filtration,Rates, Glomerular Filtration
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000831 Animals, Newborn Refers to animals in the period of time just after birth. Animals, Neonatal,Animal, Neonatal,Animal, Newborn,Neonatal Animal,Neonatal Animals,Newborn Animal,Newborn Animals

Related Publications

N B Clark, and L L Mok
September 1980, The American journal of physiology,
N B Clark, and L L Mok
October 1976, The American journal of physiology,
N B Clark, and L L Mok
February 1975, Endocrinology,
N B Clark, and L L Mok
November 1969, Metabolism: clinical and experimental,
N B Clark, and L L Mok
November 1990, Archives of disease in childhood,
N B Clark, and L L Mok
May 1970, Ceskoslovenska pediatrie,
N B Clark, and L L Mok
June 1977, Canadian journal of physiology and pharmacology,
N B Clark, and L L Mok
January 1970, The Mount Sinai journal of medicine, New York,
Copied contents to your clipboard!