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The effects of two different doses (40 and 80 mg orally) of fenfluramine on serum prolactin (PRL) levels have been evaluated in healthy and hyperprolactinemic women and compared with those of the potent dopamine antagonist sulpiride (100 mg i.m.). The lower fenfluramine dose resulted in a significant PRL rise in healthy women (n = 16) but not in hyperprolactinemics (n = 14). A dose-response effect was shown between 40 and 80 mg in control subjects (n = 7); in 4 hyperprolactinemics the higher dose also failed to increase PRL levels. Sulpiride resulted in a much greater PRL response. Since fenfluramine at the low doses used does not seem to exert antidopaminergic action, it is suggested that the mild PRL stimulation observed be mediated by the known brain serotoninergic activation induced by the drug.
C Scarduelli, and
A M Mattei, and
G Brambilla, and
C Zavaglia, and
P Adelasco, and
V Cavioni, and
C Ferrari
January 1995,
Journal of basic and clinical physiology and pharmacology,
C Scarduelli, and
A M Mattei, and
G Brambilla, and
C Zavaglia, and
P Adelasco, and
V Cavioni, and
C Ferrari
January 1988,
The Journal of clinical endocrinology and metabolism,
C Scarduelli, and
A M Mattei, and
G Brambilla, and
C Zavaglia, and
P Adelasco, and
V Cavioni, and
C Ferrari
May 2000,
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics,
C Scarduelli, and
A M Mattei, and
G Brambilla, and
C Zavaglia, and
P Adelasco, and
V Cavioni, and
C Ferrari
January 1996,
Journal of endocrinological investigation,
C Scarduelli, and
A M Mattei, and
G Brambilla, and
C Zavaglia, and
P Adelasco, and
V Cavioni, and
C Ferrari
June 1982,
Hepato-gastroenterology,
C Scarduelli, and
A M Mattei, and
G Brambilla, and
C Zavaglia, and
P Adelasco, and
V Cavioni, and
C Ferrari
September 1981,
Acta Europaea fertilitatis,
C Scarduelli, and
A M Mattei, and
G Brambilla, and
C Zavaglia, and
P Adelasco, and
V Cavioni, and
C Ferrari
October 1985,
Ginekologia polska,
C Scarduelli, and
A M Mattei, and
G Brambilla, and
C Zavaglia, and
P Adelasco, and
V Cavioni, and
C Ferrari
September 1997,
Biological psychiatry,
C Scarduelli, and
A M Mattei, and
G Brambilla, and
C Zavaglia, and
P Adelasco, and
V Cavioni, and
C Ferrari
January 1997,
Life sciences,
C Scarduelli, and
A M Mattei, and
G Brambilla, and
C Zavaglia, and
P Adelasco, and
V Cavioni, and
C Ferrari
March 1994,
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
