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This study investigated the influence of calcium on serum prolactin (PRL) in hyperprolactinemic and healthy women. Previous studies have shown an inhibitory effect of Ca2+ on serum PRL, related to the degree of hypercalcemia. Serum PRL levels were measured by immunoradiometric assay (IRMA) in subjects before and one hour after 1375 mg Ca2+ injection. Serum PRL level was significantly decreased by calcium injection in hyperprolactinemic women (89.2 +/- 29.1 and 63.3 +/- 35.8 ng/ml; p < 0.01) while it was not significant (p > 0.05) in women with normal PRL levels (12.6 +/- 5.1 ng/ml and 11.3 +/- 4.0 ng/ml). These results indicate that acute alterations in serum calcium levels affect PRL secretion in hyperprolactinemic women.
L Yildiz, and
B S Uyanik, and
S Kuşkay, and
M Küçük
May 2000,
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics,
L Yildiz, and
B S Uyanik, and
S Kuşkay, and
M Küçük
January 1985,
Gynecologic and obstetric investigation,
L Yildiz, and
B S Uyanik, and
S Kuşkay, and
M Küçük
January 1993,
Revista chilena de obstetricia y ginecologia,
L Yildiz, and
B S Uyanik, and
S Kuşkay, and
M Küçük
March 1983,
Clinical reproduction and fertility,
L Yildiz, and
B S Uyanik, and
S Kuşkay, and
M Küçük
November 1977,
The Journal of clinical endocrinology and metabolism,
L Yildiz, and
B S Uyanik, and
S Kuşkay, and
M Küçük
May 1989,
The Journal of clinical endocrinology and metabolism,
L Yildiz, and
B S Uyanik, and
S Kuşkay, and
M Küçük
July 1990,
The Journal of clinical endocrinology and metabolism,
L Yildiz, and
B S Uyanik, and
S Kuşkay, and
M Küçük
December 1975,
British medical journal,
L Yildiz, and
B S Uyanik, and
S Kuşkay, and
M Küçük
January 1984,
Hormone research,
L Yildiz, and
B S Uyanik, and
S Kuşkay, and
M Küçük
October 1987,
Fertility and sterility,
