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Helium-cold hypothermic hamsters, colonic temperature (Tc) 7 to 11 degrees C, injected with acetylcholine (ACH) at a preoptic-anterior hypothalamic (AHPOA) site responded with a rise in colonic temperature while remaining in a cold environmental chamber. The He-Cold hamster does not thermoregulate at these body temperatures. In contrast to central ACH-elicited responses, the injection of alpha and beta adrenergic drugs into the systemic circulation of the He-Cold hamster did not elicit a rise in colonic temperature. The data describe a different animal model of rewarming than has previously been described that is under pharmacologic control by the experimenter. The use of exogenous neurotransmitter provides the potential to understand the mechanisms of thermoregulation in deep experimental hypothermia.
G E Resch, and
C W Simpson
February 1975,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
G E Resch, and
C W Simpson
January 1986,
Lancet (London, England),
G E Resch, and
C W Simpson
August 1957,
Praxis,
G E Resch, and
C W Simpson
May 2001,
The American journal of nursing,
G E Resch, and
C W Simpson
August 1974,
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
G E Resch, and
C W Simpson
September 1984,
The Journal of pediatrics,
G E Resch, and
C W Simpson
December 2009,
Der Unfallchirurg,
G E Resch, and
C W Simpson
December 1956,
Science (New York, N.Y.),
G E Resch, and
C W Simpson
July 1998,
The Canadian veterinary journal = La revue veterinaire canadienne,
