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During the long-term treatment with azathioprine of 79 patients suffering from MS there was a significant reduction in the relapse rate; the course of the disease was also favorabley influenced. In about one third of the patiens afflicted with the chronic progressive form of MS, there was no further progression. After conclusion of the treatment its favorable effect lasted for 1 to 2 years; then the disease worsened, and the relapse rate increased again. Treatment with antilymphocyte globulin and/or thoracic duct drainage in 18 patients led to impressive improvement or a stabilization of the neurological signs in those with a relapsing course. The chronic progressive course of MS was arrested in about two thirds of the patients. The effect of the treatment lasted from one to several years.
E Frick, and
H Angstwurm, and
R Blomer, and
G Strauss
May 1978,
Der Nervenarzt,
E Frick, and
H Angstwurm, and
R Blomer, and
G Strauss
January 1974,
Rivista di neurobiologia : organo ufficiale della Societa dei neurologi, neuroradiologi e neurochirurghi ospedalieri,
E Frick, and
H Angstwurm, and
R Blomer, and
G Strauss
January 1976,
Postgraduate medical journal,
E Frick, and
H Angstwurm, and
R Blomer, and
G Strauss
June 1979,
Revue neurologique,
E Frick, and
H Angstwurm, and
R Blomer, and
G Strauss
January 1975,
Przeglad lekarski,
E Frick, and
H Angstwurm, and
R Blomer, and
G Strauss
August 1975,
MMW, Munchener medizinische Wochenschrift,
E Frick, and
H Angstwurm, and
R Blomer, and
G Strauss
November 1980,
Vnitrni lekarstvi,
E Frick, and
H Angstwurm, and
R Blomer, and
G Strauss
January 1978,
Postepy higieny i medycyny doswiadczalnej,
E Frick, and
H Angstwurm, and
R Blomer, and
G Strauss
June 1978,
Revista medica de Chile,
E Frick, and
H Angstwurm, and
R Blomer, and
G Strauss
February 1979,
Haematologica,
