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Twenty patients with multiple sclerosis, in whom treatment with azathioprine and steroids had not altered the progression of the disease, were given additional treatment with either antilymphocyte globulin (ALG) (seven patients), thoracic duct drainage (TDD) (five patients) or a combination of both (eight patients). Four of the seven patients treated with the addition of ALG showed remarkable improvement which has lasted little improvement. In the eight patients receiving both had severe allergic reactions to ALG which prevented adequate dosage. TDD alone was performed in patients sensitive to ALG. These five patients showed little improvement. In the eight patients receiving both ALG and TDD there was marked improvement in four patients which has again lasted several years. The main side effect of ALG therapy is allergic reactions. Major infections or tumour formation did not occur in any patients.
J Ring, and
J Seifert, and
H Anstwurm, and
E Frick, and
J Mertin, and
B Brass, and
H Backmund, and
G Lob
January 1978,
Postepy higieny i medycyny doswiadczalnej,
J Ring, and
J Seifert, and
H Anstwurm, and
E Frick, and
J Mertin, and
B Brass, and
H Backmund, and
G Lob
October 1976,
Journal of the neurological sciences,
J Ring, and
J Seifert, and
H Anstwurm, and
E Frick, and
J Mertin, and
B Brass, and
H Backmund, and
G Lob
September 1977,
MMW, Munchener medizinische Wochenschrift,
J Ring, and
J Seifert, and
H Anstwurm, and
E Frick, and
J Mertin, and
B Brass, and
H Backmund, and
G Lob
September 1979,
Bollettino dell'Istituto sieroterapico milanese,
J Ring, and
J Seifert, and
H Anstwurm, and
E Frick, and
J Mertin, and
B Brass, and
H Backmund, and
G Lob
January 1997,
Terapevticheskii arkhiv,
J Ring, and
J Seifert, and
H Anstwurm, and
E Frick, and
J Mertin, and
B Brass, and
H Backmund, and
G Lob
January 1988,
Medicina,
J Ring, and
J Seifert, and
H Anstwurm, and
E Frick, and
J Mertin, and
B Brass, and
H Backmund, and
G Lob
May 1988,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
J Ring, and
J Seifert, and
H Anstwurm, and
E Frick, and
J Mertin, and
B Brass, and
H Backmund, and
G Lob
January 1976,
Postgraduate medical journal,
J Ring, and
J Seifert, and
H Anstwurm, and
E Frick, and
J Mertin, and
B Brass, and
H Backmund, and
G Lob
January 1976,
Postgraduate medical journal,
J Ring, and
J Seifert, and
H Anstwurm, and
E Frick, and
J Mertin, and
B Brass, and
H Backmund, and
G Lob
July 1996,
Arthritis and rheumatism,
