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The effect of carminomycin on the liver energetic metabolism was studied experimentally on rats in dynamics after its intraperitoneal administration in a single LD50 and the therapeutic doses for a treatment course. It was found that changes in the rat liver tissues on the part of the energetic metabolism occurred irrespective of the antibiotic dose and the administration multiplicity. Mainly they were of reversible nature: the balance of consumption and resynthesis of the phosphate macroergs was impaired, the glycolytic processes increased, shifts in the activity of the enzymes of the pentose phosphate pathway of oxydation were observed. The level of the above changes was more pronounced when carminomycin was administered in LD50. The adrenal system played an important role in the mechanism of the shifts noted.
L A Bulanova, and
E D Gol'dberg, and
B Iu Sal'nik, and
N P Chulalina
February 1979,
Antibiotiki,
L A Bulanova, and
E D Gol'dberg, and
B Iu Sal'nik, and
N P Chulalina
August 1991,
Biochemistry international,
L A Bulanova, and
E D Gol'dberg, and
B Iu Sal'nik, and
N P Chulalina
July 2015,
Toxicology letters,
L A Bulanova, and
E D Gol'dberg, and
B Iu Sal'nik, and
N P Chulalina
January 1998,
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994),
L A Bulanova, and
E D Gol'dberg, and
B Iu Sal'nik, and
N P Chulalina
December 2015,
Zhonghua wei zhong bing ji jiu yi xue,
L A Bulanova, and
E D Gol'dberg, and
B Iu Sal'nik, and
N P Chulalina
January 1990,
The International journal of biochemistry,
L A Bulanova, and
E D Gol'dberg, and
B Iu Sal'nik, and
N P Chulalina
January 1975,
Antibiotiki,
L A Bulanova, and
E D Gol'dberg, and
B Iu Sal'nik, and
N P Chulalina
January 1978,
Zdravookhranenie Kirgizii,
L A Bulanova, and
E D Gol'dberg, and
B Iu Sal'nik, and
N P Chulalina
June 2003,
Toxicology letters,
L A Bulanova, and
E D Gol'dberg, and
B Iu Sal'nik, and
N P Chulalina
January 1987,
Physiology & behavior,
