BIOMAT Database Logo BIOMAT Database Logo

Partial purification of human liver cytochrome P 450. 1979

P Beaune, and P Dansette, and J P Flinois, and S Columelli, and D Mansuy, and J P Leroux

UI MeSH Term Description Entries
D008297 Male Males
D008862 Microsomes, Liver Closed vesicles of fragmented endoplasmic reticulum created when liver cells or tissue are disrupted by homogenization. They may be smooth or rough. Liver Microsomes,Liver Microsome,Microsome, Liver
D003577 Cytochrome P-450 Enzyme System A superfamily of hundreds of closely related HEMEPROTEINS found throughout the phylogenetic spectrum, from animals, plants, fungi, to bacteria. They include numerous complex monooxygenases (MIXED FUNCTION OXYGENASES). In animals, these P-450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs (BIOTRANSFORMATION). They are classified, according to their sequence similarities rather than functions, into CYP gene families (>40% homology) and subfamilies (>59% homology). For example, enzymes from the CYP1, CYP2, and CYP3 gene families are responsible for most drug metabolism. Cytochrome P-450,Cytochrome P-450 Enzyme,Cytochrome P-450-Dependent Monooxygenase,P-450 Enzyme,P450 Enzyme,CYP450 Family,CYP450 Superfamily,Cytochrome P-450 Enzymes,Cytochrome P-450 Families,Cytochrome P-450 Monooxygenase,Cytochrome P-450 Oxygenase,Cytochrome P-450 Superfamily,Cytochrome P450,Cytochrome P450 Superfamily,Cytochrome p450 Families,P-450 Enzymes,P450 Enzymes,Cytochrome P 450,Cytochrome P 450 Dependent Monooxygenase,Cytochrome P 450 Enzyme,Cytochrome P 450 Enzyme System,Cytochrome P 450 Enzymes,Cytochrome P 450 Families,Cytochrome P 450 Monooxygenase,Cytochrome P 450 Oxygenase,Cytochrome P 450 Superfamily,Enzyme, Cytochrome P-450,Enzyme, P-450,Enzyme, P450,Enzymes, Cytochrome P-450,Enzymes, P-450,Enzymes, P450,Monooxygenase, Cytochrome P-450,Monooxygenase, Cytochrome P-450-Dependent,P 450 Enzyme,P 450 Enzymes,P-450 Enzyme, Cytochrome,P-450 Enzymes, Cytochrome,Superfamily, CYP450,Superfamily, Cytochrome P-450,Superfamily, Cytochrome P450
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D013053 Spectrophotometry The art or process of comparing photometrically the relative intensities of the light in different parts of the spectrum.

Related Publications

P Beaune, and P Dansette, and J P Flinois, and S Columelli, and D Mansuy, and J P Leroux
[Purification of cytochrome P-450 and NADPH cytochrome p-450 reductase from human liver].
January 1990, Journal de pharmacie de Belgique,
P Beaune, and P Dansette, and J P Flinois, and S Columelli, and D Mansuy, and J P Leroux
Partial purification of cytochrome P-450 from human normal granulocytes.
February 1986, Research communications in chemical pathology and pharmacology,
P Beaune, and P Dansette, and J P Flinois, and S Columelli, and D Mansuy, and J P Leroux
Partial purification and characterization of cytochrome P-450 from human placenta.
January 1985, The International journal of biochemistry,
P Beaune, and P Dansette, and J P Flinois, and S Columelli, and D Mansuy, and J P Leroux
Isolation and partial purification of cytochrome P-450 from uninduced mouse liver.
October 1976, Biochemical and biophysical research communications,
P Beaune, and P Dansette, and J P Flinois, and S Columelli, and D Mansuy, and J P Leroux
Isolation and partial purification of cytochrome P-450 from uninduced rat liver.
March 1978, Biochemical and biophysical research communications,
P Beaune, and P Dansette, and J P Flinois, and S Columelli, and D Mansuy, and J P Leroux
Purification and characterization of human liver cytochrome P-450-ALC.
October 1987, Biochemical and biophysical research communications,
P Beaune, and P Dansette, and J P Flinois, and S Columelli, and D Mansuy, and J P Leroux
Purification and properties of cytochrome P-450 and NADPH-cytochrome c (P-450) reductase from human liver microsomes.
July 1979, Biochemical pharmacology,
P Beaune, and P Dansette, and J P Flinois, and S Columelli, and D Mansuy, and J P Leroux
Purification of a new cytochrome P-450 from human liver microsomes.
July 1985, Biochimica et biophysica acta,
P Beaune, and P Dansette, and J P Flinois, and S Columelli, and D Mansuy, and J P Leroux
Purification and characterization of human liver microsomal cytochrome P-450 2A6.
November 1991, Molecular pharmacology,
P Beaune, and P Dansette, and J P Flinois, and S Columelli, and D Mansuy, and J P Leroux
Separation, partial purification and characterization of cytochrome P-450 having different affinities for NADPH-cytochrome P-450 reductase from rat liver microsomes.
May 1985, Biochemical pharmacology,
Copied contents to your clipboard!