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Left or right stellate ganglion stimulation resulted in changes of ST segments and T waves of electrocardiogram. The present experiments were performed in an attempt to elucidate alpha-and beta-adrenergic actions, and calcium action on the monophasic action potential duration (APD), that is, the repolarizing phase of myocardium. During experiments in open-chest dogs, right ventricular pacing was performed for avoiding the acceleration of heart rate by stellate ganglion stimulation. Administration of phentolamine, propranolol or D600 prolonged APD, while hydrazine shortened it. However, stellate ganglion stimulation caused a prolongation of APD after infusion of propranolol or hydrazine, and a shortening of APD after infusion of phentolamine, D600 or hydrazine. These results indicate that alpha-and beta-adrenergic actions as well as calcium ions can be related to APD in the ventricular myocardium of dogs; apparently, alpha-adrenergic action prolongs APD and beta-adrenergic action shortens it.
T Matoba, and
H Toshima, and
K Nagae, and
S Yamazaki
June 1991,
Pacing and clinical electrophysiology : PACE,
T Matoba, and
H Toshima, and
K Nagae, and
S Yamazaki
May 2004,
Chest,
T Matoba, and
H Toshima, and
K Nagae, and
S Yamazaki
July 1985,
Pacing and clinical electrophysiology : PACE,
T Matoba, and
H Toshima, and
K Nagae, and
S Yamazaki
July 1964,
The American journal of physiology,
T Matoba, and
H Toshima, and
K Nagae, and
S Yamazaki
May 2020,
Heart rhythm,
T Matoba, and
H Toshima, and
K Nagae, and
S Yamazaki
April 1988,
Canadian journal of physiology and pharmacology,
T Matoba, and
H Toshima, and
K Nagae, and
S Yamazaki
August 1976,
The American journal of cardiology,
T Matoba, and
H Toshima, and
K Nagae, and
S Yamazaki
July 1999,
Journal of electrocardiology,
T Matoba, and
H Toshima, and
K Nagae, and
S Yamazaki
February 1998,
Japanese journal of pharmacology,
T Matoba, and
H Toshima, and
K Nagae, and
S Yamazaki
January 1999,
Scandinavian cardiovascular journal : SCJ,
