BIOMAT Database Logo BIOMAT Database Logo

Mechanism of oxidative cyclization of squalene. Evidence for cyclization of squalene from either end of the squalene molecule in the in vivo biosynthesis of fusidic acid by Fusidium coccineum. 1973

R C Ebersole, and W O Godtfredsen, and S Vagnedal, and E Caspi

UI MeSH Term Description Entries
D008722 Methods A series of steps taken in order to conduct research. Techniques,Methodological Studies,Methodological Study,Procedures,Studies, Methodological,Study, Methodological,Method,Procedure,Technique
D010084 Oxidation-Reduction A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471). Redox,Oxidation Reduction
D003500 Cyclization Changing an open-chain hydrocarbon to a closed ring. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed) Cyclizations
D003904 Mitosporic Fungi A large and heterogenous group of fungi whose common characteristic is the absence of a sexual state. Many of the pathogenic fungi in humans belong to this group. Deuteromycetes,Deuteromycota,Fungi imperfecti,Fungi, Mitosporic,Hyphomycetes,Deuteromycete,Deuteromycotas,Fungi imperfectus,Fungus, Mitosporic,Hyphomycete,Mitosporic Fungus,imperfectus, Fungi
D005672 Fusidic Acid An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed). It acts by inhibiting translocation during protein synthesis. Fucithalmic,Fusidate Sodium,Fusidic Acid, Sodium Salt,Fusidin,Silver Fusidate,Sodium Fusidate,Stanicide,Acid, Fusidic,Fusidate, Silver,Fusidate, Sodium,Sodium, Fusidate
D013185 Squalene A natural 30-carbon triterpene.

Related Publications

R C Ebersole, and W O Godtfredsen, and S Vagnedal, and E Caspi
Mechanism of squalene cyclization. The biosynthesis of fusidic acid.
April 1971, The Journal of biological chemistry,
R C Ebersole, and W O Godtfredsen, and S Vagnedal, and E Caspi
[Possible role of the respiratory system of Fusidium coccineum in regulating fusidic acid biosynthesis].
January 1980, Mikrobiologiia,
R C Ebersole, and W O Godtfredsen, and S Vagnedal, and E Caspi
Mechanism of squalene cyclization. Biosynthesis of fusidic acid from (4R)-[2-14C,43H]mevalonic acid.
January 1970, Journal of the American Chemical Society,
R C Ebersole, and W O Godtfredsen, and S Vagnedal, and E Caspi
Biosynthesis of fusidic acid from squalene 2,3-oxide.
January 1968, Journal of the American Chemical Society,
R C Ebersole, and W O Godtfredsen, and S Vagnedal, and E Caspi
[Characteristics of fucidin biosynthesis by a Fusidium coccineum 257 A strain].
January 1977, Antibiotiki,
R C Ebersole, and W O Godtfredsen, and S Vagnedal, and E Caspi
[Sporogenesis, antibiotic biosynthesis and the systematic position of Fusidium coccineum].
July 1983, Antibiotiki,
R C Ebersole, and W O Godtfredsen, and S Vagnedal, and E Caspi
[Oxidative cyclization of squalene. Biosynthesis of sterols].
February 1970, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme,
R C Ebersole, and W O Godtfredsen, and S Vagnedal, and E Caspi
The biosynthesis of beta-amyrin. Mechanism of squalene cyclization.
February 1968, The Biochemical journal,
R C Ebersole, and W O Godtfredsen, and S Vagnedal, and E Caspi
High-yield strain of fusidic acid obtained by atmospheric and room temperature plasma mutagenesis and the transcriptional changes involved in improving its production in fungus Fusidium coccineum.
February 2021, Journal of applied microbiology,
R C Ebersole, and W O Godtfredsen, and S Vagnedal, and E Caspi
[Carbohydrate and pyruvic acid degradation pathways in Fusidium coccineum strains with varying levels of antibiotic synthesis].
October 1976, Antibiotiki,
Copied contents to your clipboard!