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A combination of 5-fluorouracil, Adriamycin, cyclophosphamide, and BCG (FAC-BCG) was evaluated as adjuvant treatment in breast cancer patients following surgical excision and/or radiation of first site of recurrent disease. In a group of 68 patients treated with FAC-BCG, the estimated proportion remaining free of disease at 2 years from first recurrence was 69%, compared to 24% in 60 historical control patients (P less than 0.01). Estimated 2-year survival rate from first recurrence was 85% for the FAC-BCG patients and 78% for the controls (P = 0.07). This regimen has significantly prolonged the disease-free interval from the first recurrence, but additional follow-up is needed to determine its effect on long-term survival.
A U Buzdar, and
G R Blumenschein, and
T L Smith, and
C K Tashima, and
G N Hortobagyi, and
H Y Yap, and
J U Gutterman, and
E M Hersh, and
E A Gehan
January 1999,
Breast cancer research and treatment,
A U Buzdar, and
G R Blumenschein, and
T L Smith, and
C K Tashima, and
G N Hortobagyi, and
H Y Yap, and
J U Gutterman, and
E M Hersh, and
E A Gehan
February 1996,
Seminars in oncology,
A U Buzdar, and
G R Blumenschein, and
T L Smith, and
C K Tashima, and
G N Hortobagyi, and
H Y Yap, and
J U Gutterman, and
E M Hersh, and
E A Gehan
February 1998,
Journal of clinical oncology : official journal of the American Society of Clinical Oncology,
A U Buzdar, and
G R Blumenschein, and
T L Smith, and
C K Tashima, and
G N Hortobagyi, and
H Y Yap, and
J U Gutterman, and
E M Hersh, and
E A Gehan
September 2019,
The Lancet. Oncology,
A U Buzdar, and
G R Blumenschein, and
T L Smith, and
C K Tashima, and
G N Hortobagyi, and
H Y Yap, and
J U Gutterman, and
E M Hersh, and
E A Gehan
October 1976,
Archives of surgery (Chicago, Ill. : 1960),
A U Buzdar, and
G R Blumenschein, and
T L Smith, and
C K Tashima, and
G N Hortobagyi, and
H Y Yap, and
J U Gutterman, and
E M Hersh, and
E A Gehan
July 2010,
Surgical oncology clinics of North America,
A U Buzdar, and
G R Blumenschein, and
T L Smith, and
C K Tashima, and
G N Hortobagyi, and
H Y Yap, and
J U Gutterman, and
E M Hersh, and
E A Gehan
January 2008,
Cancer treatment and research,
A U Buzdar, and
G R Blumenschein, and
T L Smith, and
C K Tashima, and
G N Hortobagyi, and
H Y Yap, and
J U Gutterman, and
E M Hersh, and
E A Gehan
May 1990,
Cancer,
A U Buzdar, and
G R Blumenschein, and
T L Smith, and
C K Tashima, and
G N Hortobagyi, and
H Y Yap, and
J U Gutterman, and
E M Hersh, and
E A Gehan
December 1993,
British journal of cancer,
A U Buzdar, and
G R Blumenschein, and
T L Smith, and
C K Tashima, and
G N Hortobagyi, and
H Y Yap, and
J U Gutterman, and
E M Hersh, and
E A Gehan
February 2010,
Clinical oncology (Royal College of Radiologists (Great Britain)),
