BIOMAT Database Logo BIOMAT Database Logo

Electronic structure and reactivity of four stereo isomers of benzo(a)pyrene 7,8-diol-9,10-epoxide. 1979

O Kikuchi, and A J Hopfinger, and G Klopman

UI MeSH Term Description Entries
D008968 Molecular Conformation The characteristic three-dimensional shape of a molecule. Molecular Configuration,3D Molecular Structure,Configuration, Molecular,Molecular Structure, Three Dimensional,Three Dimensional Molecular Structure,3D Molecular Structures,Configurations, Molecular,Conformation, Molecular,Conformations, Molecular,Molecular Configurations,Molecular Conformations,Molecular Structure, 3D,Molecular Structures, 3D,Structure, 3D Molecular,Structures, 3D Molecular
D004852 Epoxy Compounds Organic compounds that include a cyclic ether with three ring atoms in their structure. They are commonly used as precursors for POLYMERS such as EPOXY RESINS. Epoxide,Epoxides,Epoxy Compound,Oxiranes,Compound, Epoxy,Compounds, Epoxy
D000641 Ammonia A colorless alkaline gas. It is formed in the body during decomposition of organic materials during a large number of metabolically important reactions. Note that the aqueous form of ammonia is referred to as AMMONIUM HYDROXIDE.
D001580 Benzopyrenes A class of chemicals that contain an anthracene ring with a naphthalene ring attached to it. Benzpyrene
D013237 Stereoisomerism The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed) Molecular Stereochemistry,Stereoisomers,Stereochemistry, Molecular,Stereoisomer
D013329 Structure-Activity Relationship The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups. Relationship, Structure-Activity,Relationships, Structure-Activity,Structure Activity Relationship,Structure-Activity Relationships

Related Publications

O Kikuchi, and A J Hopfinger, and G Klopman
Chromatographic characterization of hemoglobin benzo[a]pyrene-7,8-diol-9,10-epoxide adducts.
January 1996, Fundamental and applied toxicology : official journal of the Society of Toxicology,
O Kikuchi, and A J Hopfinger, and G Klopman
Preferential modification of GC boxes by benzo[a]pyrene-7,8-diol-9,10-epoxide.
January 1989, Molecular carcinogenesis,
O Kikuchi, and A J Hopfinger, and G Klopman
Fungal oxidation of benzo[a]pyrene and (+/-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene. Evidence for the formation of a benzo[a]pyrene 7,8-diol-9,10-epoxide.
June 1980, The Journal of biological chemistry,
O Kikuchi, and A J Hopfinger, and G Klopman
Benzo[a]pyrene-7,8-diol-9,10-epoxide-DNA adducts and increased p53 protein in mouse skin.
April 1994, Carcinogenesis,
O Kikuchi, and A J Hopfinger, and G Klopman
Synthesis and hydrolysis of a cis-chlorohydrin derived from a benzo[a]pyrene 7,8-diol 9,10-epoxide.
November 2004, The Journal of organic chemistry,
O Kikuchi, and A J Hopfinger, and G Klopman
Mechanisms of reaction of benzo(a)pyrene-7,8-diol-9,10-epoxide with DNA in aqueous solutions.
August 1984, Biophysical chemistry,
O Kikuchi, and A J Hopfinger, and G Klopman
Crystal and molecular structure of a benzo[a]pyrene 7,8-diol 9,10-epoxide N2-deoxyguanosine adduct: absolute configuration and conformation.
February 2004, Proceedings of the National Academy of Sciences of the United States of America,
O Kikuchi, and A J Hopfinger, and G Klopman
Molecular characterization of mutation and comparison of mutation profiles in the hprt gene of Chinese hamster ovary cells treated with benzo[a]pyrene trans-7,8-diol-anti-9,10-epoxide, 1-nitrobenzo[a]pyrene trans-7,8-diol-anti-9,10-epoxide, and 3-nitrobenzo[a]pyrene trans-7,8- diol-anti-9,10-epoxide.
January 1996, Environmental and molecular mutagenesis,
O Kikuchi, and A J Hopfinger, and G Klopman
Differential c-myc expression profiles in normal human bronchial epithelial cells following treatment with benzo[a]pyrene, benzo[a]pyrene-4,5 epoxide, and benzo[a]pyrene-7,8-9,10 diol epoxide.
June 2004, Molecular carcinogenesis,
O Kikuchi, and A J Hopfinger, and G Klopman
Glutathione transferase catalyzed conjugation of benzo[a]pyrene 7,8-diol 9,10-epoxide with glutathione in human skin.
January 1989, Chemico-biological interactions,
Copied contents to your clipboard!