Biomaterial Database

Uptake and excretion of 60Co by black bullheads Ictalurus melas (Rafinesque). 1971

J R Reed

Black bullheads were able to accumulate 60Co from water. During uptake the gills contained from 19% to 30% of the whole-body 60Co activity. After 3 days of 60Co uptake the flesh accounted for 16% of the total activity. Fish that were dosed in a single feeding lost 95.5% of the initial activity in one day of excretion whereas fish that were exposed in 60Co-dosed water lost 28% of the initial activity during the first day of excretion. Elimination of 60Co after intake from water or from food occurred in three components. The initial rapid loss of activity after uptake from food had a biological half-life of 1.5 days, compared to 3.4 days for the initial component after uptake via water. The intermediate components had biological half-lives of 35 and 40.5 days, respectively, after water uptake and after food uptake. The third components in both cases had long, undetermined biological half-lives. Radiocobalt and stable cobalt analyses showed that the blood and blood-rich organs, particularly the kidney, were principal sites of cobalt concentration.

UI	MeSH Term	Description	Entries
D003037	Cobalt Radioisotopes	Unstable isotopes of cobalt that decay or disintegrate emitting radiation. Co atoms with atomic weights of 54-64, except 59, are radioactive cobalt isotopes.	Radioisotopes, Cobalt
D005399	Fishes	A group of cold-blooded, aquatic vertebrates having gills, fins, a cartilaginous or bony endoskeleton, and elongated bodies covered with scales.
D006207	Half-Life	The time it takes for a substance (drug, radioactive nuclide, or other) to lose half of its pharmacologic, physiologic, or radiologic activity.	Halflife,Half Life,Half-Lifes,Halflifes
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013714	Tennessee	State bounded on the north by Kentucky and Virginia, on the east by North Carolina, on the south by Georgia, Alabama and Mississippi, and on the west by Arkansas and Missouri.
D014018	Tissue Distribution	Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.	Distribution, Tissue,Distributions, Tissue,Tissue Distributions
D014878	Water Pollution, Radioactive	Contamination of water with radioactive materials and/or substances.	Pollution, Radioactive Water,Radioactive Water Pollution