The neuromuscular blocking properties of the antimalarial agent, bis((chloro-7"-quinolyl-4")amino-2'-propyl)-1,4-piperazine. 1970

T R Castles, and E Loth, and C R Crawford, and C C Lee

UI MeSH Term Description Entries
D007082 Ileum The distal and narrowest portion of the SMALL INTESTINE, between the JEJUNUM and the ILEOCECAL VALVE of the LARGE INTESTINE.
D008274 Magnesium A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
D008297 Male Males
D009119 Muscle Contraction A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments. Inotropism,Muscular Contraction,Contraction, Muscle,Contraction, Muscular,Contractions, Muscle,Contractions, Muscular,Inotropisms,Muscle Contractions,Muscular Contractions
D009132 Muscles Contractile tissue that produces movement in animals. Muscle Tissue,Muscle,Muscle Tissues,Tissue, Muscle,Tissues, Muscle
D009467 Neuromuscular Depolarizing Agents Drugs that interrupt transmission at the skeletal neuromuscular junction by causing sustained depolarization of the motor end plate. These agents are primarily used as adjuvants in surgical anesthesia to cause skeletal muscle relaxation. Depolarizing Muscle Relaxants,Muscle Relaxants, Depolarizing,Depolarizing Blockers,Agents, Neuromuscular Depolarizing,Blockers, Depolarizing,Depolarizing Agents, Neuromuscular,Relaxants, Depolarizing Muscle
D010710 Phosphates Inorganic salts of phosphoric acid. Inorganic Phosphate,Phosphates, Inorganic,Inorganic Phosphates,Orthophosphate,Phosphate,Phosphate, Inorganic
D010791 Phrenic Nerve The motor nerve of the diaphragm. The phrenic nerve fibers originate in the cervical spinal column (mostly C4) and travel through the cervical plexus to the diaphragm. Nerve, Phrenic,Nerves, Phrenic,Phrenic Nerves
D010879 Piperazines Compounds that are derived from PIPERAZINE.
D011188 Potassium An element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.

Related Publications

T R Castles, and E Loth, and C R Crawford, and C C Lee
September 1969, Toxicology and applied pharmacology,
T R Castles, and E Loth, and C R Crawford, and C C Lee
January 2005, Bioorganic & medicinal chemistry letters,
T R Castles, and E Loth, and C R Crawford, and C C Lee
February 2009, Journal of enzyme inhibition and medicinal chemistry,
T R Castles, and E Loth, and C R Crawford, and C C Lee
February 2003, Journal of medicinal chemistry,
T R Castles, and E Loth, and C R Crawford, and C C Lee
May 1981, Bollettino chimico farmaceutico,
T R Castles, and E Loth, and C R Crawford, and C C Lee
December 2015, Acta crystallographica. Section E, Crystallographic communications,
T R Castles, and E Loth, and C R Crawford, and C C Lee
December 2010, Acta crystallographica. Section E, Structure reports online,
T R Castles, and E Loth, and C R Crawford, and C C Lee
November 2009, Acta crystallographica. Section E, Structure reports online,
T R Castles, and E Loth, and C R Crawford, and C C Lee
May 2010, Acta crystallographica. Section E, Structure reports online,
Copied contents to your clipboard!