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The addition of K2Cr2O7, at concentrations ranging from 0.1 to 0.5 microng/ml, to hamster total embryonic cells for 24 h, resulted in consistent and drastic chromosomal aberrations including gaps, breaks and exchanges. The above effect, however, was reduced successfully by the addition of a reducing agent, Na2SO3. Among other chromium compounds examined, divalent and trivalent chromium salts were ineffective on chromosome morphology even at a concentration of 3.5 microng/ml as chromium, whereas a hexavalent compound, CrO3, was highly effective. K2Cr2O7 also enhanced the morphological transformation rate in a short-term colony assay, in whicy hamster embryonic cells (1x10(4) cells/60-mm dish) were treated and the morphology was observed 8 to 10 days after the treatment.
H Tsuda, and
K Kato
August 1992,
Cancer genetics and cytogenetics,
H Tsuda, and
K Kato
June 1977,
Mutation research,
H Tsuda, and
K Kato
July 1979,
Mutation research,
H Tsuda, and
K Kato
July 1979,
Cancer research,
H Tsuda, and
K Kato
December 1973,
Cancer research,
H Tsuda, and
K Kato
October 1982,
Chemico-biological interactions,
H Tsuda, and
K Kato
February 1978,
Gan,
H Tsuda, and
K Kato
December 2009,
Investigative ophthalmology & visual science,
H Tsuda, and
K Kato
July 1979,
Mutation research,
H Tsuda, and
K Kato
January 1977,
Experientia,
