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Morphological and behavioral responses to estradiol-17 beta (E2-17 beta) and estradiol-17 alpha (E2-17 alpha) were examined in a series of three experiments. The E2-17 beta augmented uterine growth in hamsters to a greater extent than did E2-17 alpha. Lordosis in ovariectomized adults was elicited by treatment with E2-17 beta but not with E2-17 alpha (each tested in combination with progesterone). When administered neonatally only E2-17 beta disrupted estrous cyclicity in the intact female and induced the ability to mount in ovariectomized, androgen-treated adults. These results suggest the existence of a stereospecific response to estrogenic stimulation in neural tissue comparable with that occurring in the uterus.
J M Whitsett, and
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G M Bediz
December 1988,
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J M Whitsett, and
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G M Bediz
February 1992,
Behavioral neuroscience,
J M Whitsett, and
L E Gray, and
G M Bediz
January 1990,
Physiology & behavior,
J M Whitsett, and
L E Gray, and
G M Bediz
September 1986,
Behavioral and neural biology,
J M Whitsett, and
L E Gray, and
G M Bediz
June 1981,
Pharmacology, biochemistry, and behavior,
J M Whitsett, and
L E Gray, and
G M Bediz
January 2009,
Hormones and behavior,
J M Whitsett, and
L E Gray, and
G M Bediz
April 1997,
The American journal of physiology,
J M Whitsett, and
L E Gray, and
G M Bediz
April 1984,
Physiology & behavior,
J M Whitsett, and
L E Gray, and
G M Bediz
April 2011,
The Journal of neuroscience : the official journal of the Society for Neuroscience,
J M Whitsett, and
L E Gray, and
G M Bediz
September 1986,
Behavioral and neural biology,
