[Immunoelectrophoretic studies of the antigenic properties of virulent and vaccinal Newcastle strains]. 1977

P Danchev

Studied were immunoelectrophoretically the antigenic properties of 16 virulent and 4 vaccinal strains of the Newcastle disease virus--B1, La Sota, Komarov, and Roakin. Results showed that all virulent strains isolated in the course of 5 years had the same antigenic components as compared both to each other and to the vaccinal strains. This similarity was manifested by the presence of a clearly expressed precipitation line found with all strains in one and the same place of the immunoelectrophoregrams. It was assumed on the basis of the results obtained that there is no variation in the antigenic structure of the Newcastle disease virus. This confirmed the appropriateness in using the vaccinal strains B1, La Sota, Komarov, and Roakin in the active prophylaxis of birds against Newcastle disease.

UI MeSH Term Description Entries
D007122 Immunoelectrophoresis A technique that combines protein electrophoresis and double immunodiffusion. In this procedure proteins are first separated by gel electrophoresis (usually agarose), then made visible by immunodiffusion of specific antibodies. A distinct elliptical precipitin arc results for each protein detectable by the antisera.
D009522 Newcastle disease virus The most well known avian paramyxovirus in the genus AVULAVIRUS and the cause of a highly infectious pneumoencephalitis in fowl. It is also reported to cause CONJUNCTIVITIS in humans. Transmission is by droplet inhalation or ingestion of contaminated water or food. Avian Paramyxovirus 1,Paramyxovirus 1, Avian
D000956 Antigens, Viral Substances elaborated by viruses that have antigenic activity. Viral Antigen,Viral Antigens,Antigen, Viral
D014765 Viral Vaccines Suspensions of attenuated or killed viruses administered for the prevention or treatment of infectious viral disease. Viral Vaccine,Vaccine, Viral,Vaccines, Viral
D014774 Virulence The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS. Pathogenicity

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