-transparent.png){kind=logo}
Single doses of cefmenoxime (CMX), 1 g intravenous drip infusion, were administrated to 5 patients with pleural effusion. The study group consisted of 3 men and 2 women, aged 38 to 69 years (mean 54.8 years); 4 had carcinoma with pleural effusion and 1 had SLE. Pleural fluid and serum samples were taken at intervals 1 to 24 hours for determination of CMX levels. The following results were obtained: Intravenous drip infusion of 1 g CMX yielded a peak pleural concentration of 4.5 micrograms/ml after 2 hours and pleural levels over 3 micrograms/ml were maintained for 5.5 hours after intravenous drip administration. Ratio maximum pleural concentration to peak serum level reached 15.0 +/- 8.3% at 2 hours after intravenous drip administration.
N Miyazaki, and
A Kajiki, and
H Yamazaki, and
S Harada, and
M Kido, and
A Kuroiwa
June 1977,
Antimicrobial agents and chemotherapy,
N Miyazaki, and
A Kajiki, and
H Yamazaki, and
S Harada, and
M Kido, and
A Kuroiwa
April 1993,
Journal of chemotherapy (Florence, Italy),
N Miyazaki, and
A Kajiki, and
H Yamazaki, and
S Harada, and
M Kido, and
A Kuroiwa
October 1986,
The Journal of antimicrobial chemotherapy,
N Miyazaki, and
A Kajiki, and
H Yamazaki, and
S Harada, and
M Kido, and
A Kuroiwa
November 1983,
The Journal of antimicrobial chemotherapy,
N Miyazaki, and
A Kajiki, and
H Yamazaki, and
S Harada, and
M Kido, and
A Kuroiwa
May 1986,
Antimicrobial agents and chemotherapy,
N Miyazaki, and
A Kajiki, and
H Yamazaki, and
S Harada, and
M Kido, and
A Kuroiwa
March 1979,
The Journal of antimicrobial chemotherapy,
N Miyazaki, and
A Kajiki, and
H Yamazaki, and
S Harada, and
M Kido, and
A Kuroiwa
May 1990,
Antimicrobial agents and chemotherapy,
N Miyazaki, and
A Kajiki, and
H Yamazaki, and
S Harada, and
M Kido, and
A Kuroiwa
June 1983,
Antimicrobial agents and chemotherapy,
N Miyazaki, and
A Kajiki, and
H Yamazaki, and
S Harada, and
M Kido, and
A Kuroiwa
December 1984,
The American journal of medicine,
N Miyazaki, and
A Kajiki, and
H Yamazaki, and
S Harada, and
M Kido, and
A Kuroiwa
January 1980,
The Journal of antimicrobial chemotherapy,
