-transparent.png){kind=logo}
We have identified cloned populations of trypanosomes, derived from different original field isolates and species, which appeared to possess similar variable surface-antigen types when assayed by immune lysis and immunofluorescence tests. Variable surface glycoproteins (VSGs) were isolated from these 'isotypic' trypanosomes. Isolated VSGs had identical apparent mol. wt of 60,000 but different isoelectric points. Radioimmunoassay, using 125I-labelled VSGs and rabbit anti-VSG sera, showed that isotypic VSGs contained not only the cross-reacting determinants found in all other VSGs (Barbet & McGuire, 1978) but also other cross-reacting determinants shared between isotypes. Peptide mapping revealed extensive amino-acid sequence homology between isotype VSGs.
T Vervoort, and
A F Barbet, and
A J Musoke, and
E Magnus, and
G Mpimbaza, and
N Van Meirvenne
June 1994,
Experimental parasitology,
T Vervoort, and
A F Barbet, and
A J Musoke, and
E Magnus, and
G Mpimbaza, and
N Van Meirvenne
January 1982,
Advances in parasitology,
T Vervoort, and
A F Barbet, and
A J Musoke, and
E Magnus, and
G Mpimbaza, and
N Van Meirvenne
August 1987,
FEBS letters,
T Vervoort, and
A F Barbet, and
A J Musoke, and
E Magnus, and
G Mpimbaza, and
N Van Meirvenne
January 1984,
Oxford surveys on eukaryotic genes,
T Vervoort, and
A F Barbet, and
A J Musoke, and
E Magnus, and
G Mpimbaza, and
N Van Meirvenne
January 1984,
Biochemical Society symposium,
T Vervoort, and
A F Barbet, and
A J Musoke, and
E Magnus, and
G Mpimbaza, and
N Van Meirvenne
December 2004,
The Journal of biological chemistry,
T Vervoort, and
A F Barbet, and
A J Musoke, and
E Magnus, and
G Mpimbaza, and
N Van Meirvenne
February 1982,
Gene,
T Vervoort, and
A F Barbet, and
A J Musoke, and
E Magnus, and
G Mpimbaza, and
N Van Meirvenne
July 1984,
Molecular and biochemical parasitology,
T Vervoort, and
A F Barbet, and
A J Musoke, and
E Magnus, and
G Mpimbaza, and
N Van Meirvenne
October 1985,
Molecular and biochemical parasitology,
T Vervoort, and
A F Barbet, and
A J Musoke, and
E Magnus, and
G Mpimbaza, and
N Van Meirvenne
July 1985,
Science (New York, N.Y.),
