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To compare the efficacy of Tc-99m HMDP and Tc-99m MDP to define skeletal lesions, 28 adult patients were examined in a double-blind, randomized, crossover study. Each patient was imaged with both agents over a period of 7-14 days. Both quantitative and qualitative evaluations were performed on the resulting images. Both agents detected the same number of skeletal lesions, and the number of lesions detected was the same whether the imaging was performed 2 or 4 hr after injection. Relative uptake of the tracer in the lesion relative to normal bone was also the same for both agents. Lesions were easier to see at 4 hr after injection than at 2 hr, presumably because soft-tissue levels were lower. Retention of tracer in bone compared with soft tissue was greater, and image quality was judged to be better, with Tc-99m HMDP than with Tc-99m MDP.
B F Van Duzee, and
J A Schaefer, and
J D Ball, and
H M Chilton, and
R J Cowan, and
C Kuni, and
R Trow, and
N E Watson
April 1983,
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
B F Van Duzee, and
J A Schaefer, and
J D Ball, and
H M Chilton, and
R J Cowan, and
C Kuni, and
R Trow, and
N E Watson
March 1982,
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
B F Van Duzee, and
J A Schaefer, and
J D Ball, and
H M Chilton, and
R J Cowan, and
C Kuni, and
R Trow, and
N E Watson
February 1979,
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
B F Van Duzee, and
J A Schaefer, and
J D Ball, and
H M Chilton, and
R J Cowan, and
C Kuni, and
R Trow, and
N E Watson
November 1983,
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
B F Van Duzee, and
J A Schaefer, and
J D Ball, and
H M Chilton, and
R J Cowan, and
C Kuni, and
R Trow, and
N E Watson
October 2021,
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
B F Van Duzee, and
J A Schaefer, and
J D Ball, and
H M Chilton, and
R J Cowan, and
C Kuni, and
R Trow, and
N E Watson
August 1981,
Clinical nuclear medicine,
B F Van Duzee, and
J A Schaefer, and
J D Ball, and
H M Chilton, and
R J Cowan, and
C Kuni, and
R Trow, and
N E Watson
May 1980,
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
B F Van Duzee, and
J A Schaefer, and
J D Ball, and
H M Chilton, and
R J Cowan, and
C Kuni, and
R Trow, and
N E Watson
June 1981,
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
B F Van Duzee, and
J A Schaefer, and
J D Ball, and
H M Chilton, and
R J Cowan, and
C Kuni, and
R Trow, and
N E Watson
August 1977,
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
B F Van Duzee, and
J A Schaefer, and
J D Ball, and
H M Chilton, and
R J Cowan, and
C Kuni, and
R Trow, and
N E Watson
June 1983,
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
