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During two large outbreaks, ten episodes of histoplasmosis were documented in eight renal allograft recipients. Another episode occurred before the outbreaks. Associated infections with cytomegalovirus occurred in five patients and may have further impaired cellular immunity. Prolonged fever was the predominant clinical finding; and dissemination was observed in seven of our nine patients, including three with meningitis. Special stains of tissues and the histoplasmal complement fixation test provided useful diagnostic information rapidly, while cultures were eventually positive in seven patients. Treatment with amphotericin B resulted in prompt clinical improvement in all patients, but relapse occurred in two patients one year following therapy.
L J Wheat, and
E J Smith, and
B Sathapatayavongs, and
B Batteiger, and
R S Filo, and
S B Leapman, and
M V French
April 1996,
Clinical transplantation,
L J Wheat, and
E J Smith, and
B Sathapatayavongs, and
B Batteiger, and
R S Filo, and
S B Leapman, and
M V French
March 1983,
Medicine,
L J Wheat, and
E J Smith, and
B Sathapatayavongs, and
B Batteiger, and
R S Filo, and
S B Leapman, and
M V French
September 1983,
Medicine,
L J Wheat, and
E J Smith, and
B Sathapatayavongs, and
B Batteiger, and
R S Filo, and
S B Leapman, and
M V French
July 1984,
Medicine,
L J Wheat, and
E J Smith, and
B Sathapatayavongs, and
B Batteiger, and
R S Filo, and
S B Leapman, and
M V French
August 1987,
Transplantation proceedings,
L J Wheat, and
E J Smith, and
B Sathapatayavongs, and
B Batteiger, and
R S Filo, and
S B Leapman, and
M V French
May 1979,
American journal of surgery,
L J Wheat, and
E J Smith, and
B Sathapatayavongs, and
B Batteiger, and
R S Filo, and
S B Leapman, and
M V French
October 2014,
Clinical transplantation,
L J Wheat, and
E J Smith, and
B Sathapatayavongs, and
B Batteiger, and
R S Filo, and
S B Leapman, and
M V French
March 2014,
Indian journal of nephrology,
L J Wheat, and
E J Smith, and
B Sathapatayavongs, and
B Batteiger, and
R S Filo, and
S B Leapman, and
M V French
July 2013,
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia,
L J Wheat, and
E J Smith, and
B Sathapatayavongs, and
B Batteiger, and
R S Filo, and
S B Leapman, and
M V French
April 1984,
Transplantation proceedings,
