-transparent.png){kind=logo}
During two histoplasmosis outbreaks in Indianapolis 45 patients presented with pericarditis. The pericarditis occurred as a late complication in individual patients and during the outbreak. Risk factors for this complication included young age, immunocompetence, and male sex in persons between 20 and 39 years old. Intrathoracic adenopathy was present in 66% of cases. Since cultures were uniformly negative, including pericardial fluid or tissue from nine patients, serologic studies provided the basis for diagnosis. Although the course was usually benign, nine patients presented with tamponade and another with constrictive pericarditis. Prompt response to antiinflammatory medications and failure to identify H. capsulatum in the pericardial fluid or tissue support a noninfectious, inflammatory mechanism for this complication. Of 20 patients reexamined 1 year later, none had evidence of constriction but three had pericardial thickening by echocardiography. Histoplasmosis should be considered in patients with pericarditis from endemic areas, particularly when associated with intrathoracic adenopathy.
L J Wheat, and
L Stein, and
B C Corya, and
J L Wass, and
J A Norton, and
K Grider, and
T G Slama, and
M L French, and
R B Kohler
September 1983,
Medicine,
L J Wheat, and
L Stein, and
B C Corya, and
J L Wass, and
J A Norton, and
K Grider, and
T G Slama, and
M L French, and
R B Kohler
April 1983,
Archives of internal medicine,
L J Wheat, and
L Stein, and
B C Corya, and
J L Wass, and
J A Norton, and
K Grider, and
T G Slama, and
M L French, and
R B Kohler
July 1984,
Medicine,
L J Wheat, and
L Stein, and
B C Corya, and
J L Wass, and
J A Norton, and
K Grider, and
T G Slama, and
M L French, and
R B Kohler
September 2003,
Annales de medecine interne,
L J Wheat, and
L Stein, and
B C Corya, and
J L Wass, and
J A Norton, and
K Grider, and
T G Slama, and
M L French, and
R B Kohler
May 2003,
Enfermedades infecciosas y microbiologia clinica,
L J Wheat, and
L Stein, and
B C Corya, and
J L Wass, and
J A Norton, and
K Grider, and
T G Slama, and
M L French, and
R B Kohler
July 1959,
Journal of the American Medical Association,
L J Wheat, and
L Stein, and
B C Corya, and
J L Wass, and
J A Norton, and
K Grider, and
T G Slama, and
M L French, and
R B Kohler
March 1981,
Annals of internal medicine,
L J Wheat, and
L Stein, and
B C Corya, and
J L Wass, and
J A Norton, and
K Grider, and
T G Slama, and
M L French, and
R B Kohler
January 2012,
Internal medicine (Tokyo, Japan),
L J Wheat, and
L Stein, and
B C Corya, and
J L Wass, and
J A Norton, and
K Grider, and
T G Slama, and
M L French, and
R B Kohler
December 1997,
Journal of emergency nursing,
L J Wheat, and
L Stein, and
B C Corya, and
J L Wass, and
J A Norton, and
K Grider, and
T G Slama, and
M L French, and
R B Kohler
July 1977,
Canadian Medical Association journal,
