-transparent.png){kind=logo}
Gossypol, a polyphenolic compound found in cotton plants, has many potential uses, including use as a male antifertility drug and spermicide. Gossypol affects a variety of cell processes and many of these effects may be explained by a common underlying mechanism. Here we report that gossypol promotes the formation of oxygen radicals when incubated with rat liver microsomes and human sperm suggesting that oxygen radical production may be the underlying basis of its biological activity.
Related Publications
A de Peyster, and
A Quintanilha, and
L Packer, and
M T Smith
January 1986,
Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao,
A de Peyster, and
A Quintanilha, and
L Packer, and
M T Smith
January 1994,
Free radical research,
A de Peyster, and
A Quintanilha, and
L Packer, and
M T Smith
February 1983,
Toxicology letters,
A de Peyster, and
A Quintanilha, and
L Packer, and
M T Smith
January 1983,
Biochemical and biophysical research communications,
A de Peyster, and
A Quintanilha, and
L Packer, and
M T Smith
October 1995,
Molecular and cellular biochemistry,
A de Peyster, and
A Quintanilha, and
L Packer, and
M T Smith
January 1988,
Basic life sciences,
A de Peyster, and
A Quintanilha, and
L Packer, and
M T Smith
February 1977,
Chemico-biological interactions,
A de Peyster, and
A Quintanilha, and
L Packer, and
M T Smith
January 1987,
Drug metabolism and disposition: the biological fate of chemicals,
A de Peyster, and
A Quintanilha, and
L Packer, and
M T Smith
April 1977,
Biochemical pharmacology,
A de Peyster, and
A Quintanilha, and
L Packer, and
M T Smith
March 1985,
Biochemical pharmacology,
