Biomaterial Database

Hexamitiasis in a laboratory mouse colony. 1978

R E Flatt, and J A Halvorsen, and R L Kemp

An acute fatal disease occurred in a mouse colony at the authors' institution. The disease caused 50% mortality among weanling mice, and was characterized clinically by depression, rough hair coat, and distention of the abdomen. The most prominent gross lesions were watery fluid and gas in the small intestine. Numerous organisms identified as Hexamita muris were seen in direct smears of the intestinal fluid. Microscopic and electron microscopic examination revealed the same organisms in the intestinal crypts, within the mucosal epithelium, and in the lamina propria. Treatment with dimetridazole controlled the clinical disease but did not eliminate the infection.

UI	MeSH Term	Description	Entries
D007421	Intestine, Small	The portion of the GASTROINTESTINAL TRACT between the PYLORUS of the STOMACH and the ILEOCECAL VALVE of the LARGE INTESTINE. It is divisible into three portions: the DUODENUM, the JEJUNUM, and the ILEUM.	Small Intestine,Intestines, Small,Small Intestines
D011528	Protozoan Infections	Infections with unicellular organisms formerly members of the subkingdom Protozoa.	Histomoniasis,Infections, Protozoan,Histomoniases,Infection, Protozoan,Protozoan Infection
D011529	Protozoan Infections, Animal	Infections with unicellular organisms formerly members of the subkingdom Protozoa. The infections may be experimental or veterinary.	Animal Protozoan Infection,Animal Protozoan Infections,Infection, Animal Protozoan,Infections, Animal Protozoan,Protozoan Infection, Animal
D004131	Dimetridazole	A compound used to treat histomoniasis in poultry.	Emtryl
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D000830	Animals, Laboratory	Animals used or intended for use in research, testing, or teaching.	Laboratory Animals,Animal, Laboratory,Laboratory Animal
D012376	Rodent Diseases	Diseases of rodents of the order RODENTIA. This term includes diseases of Sciuridae (squirrels), Geomyidae (gophers), Heteromyidae (pouched mice), Castoridae (beavers), Cricetidae (rats and mice), Muridae (Old World rats and mice), Erethizontidae (porcupines), and Caviidae (guinea pigs).	Disease, Rodent,Diseases, Rodent,Rodent Disease
D051379	Mice	The common name for the genus Mus.	Mice, House,Mus,Mus musculus,Mice, Laboratory,Mouse,Mouse, House,Mouse, Laboratory,Mouse, Swiss,Mus domesticus,Mus musculus domesticus,Swiss Mice,House Mice,House Mouse,Laboratory Mice,Laboratory Mouse,Mice, Swiss,Swiss Mouse,domesticus, Mus musculus
D056890	Eukaryota	One of the three domains of life (the others being BACTERIA and ARCHAEA), also called Eukarya. These are organisms whose cells are enclosed in membranes and possess a nucleus. They comprise almost all multicellular and many unicellular organisms, and are traditionally divided into groups (sometimes called kingdoms) including ANIMALS; PLANTS; FUNGI; and various algae and other taxa that were previously part of the old kingdom Protista.	Eukaryotes,Eucarya,Eukarya,Eukaryotas,Eukaryote