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Extensive studies have demonstrated that immune complexes represent an important affidable tumor marker with a significant value as diagnostic and prognostic indicator of malignant diseases. In this view, we have studied a group of 11 healthy donors and a group of 11 patients with gynecological malignancies, pre- and post-operatively. Blood samples stored at -30 degrees C were tested by a new competitive immunoenzymatic assay (C3bi test). The data obtained, showed significant differences between healthy donors and tumor patients (p less than 0.001). Furthermore it is notable that the results obtained pre- and post-operatively could be proved with further longitudinal studies.
B Neri, and
T Comparini, and
M Brogioni, and
O Chieffi, and
M Fabbiani
October 1982,
American journal of reproductive immunology : AJRI : official journal of the American Society for the Immunology of Reproduction and the International Coordination Committee for Immunology of Reproduction,
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October 1983,
Gynecologic oncology,
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M Fabbiani
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Experimental hematology & oncology,
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B Neri, and
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M Fabbiani
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